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Merck
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91204

Supelco

乙酸酐

for GC derivatization, LiChropur, ≥99.0%

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About This Item

線性公式:
(CH3CO)2O
CAS號碼:
分子量::
102.09
Beilstein:
385737
EC號碼:
MDL號碼:
分類程式碼代碼:
12000000
PubChem物質ID:
NACRES:
NA.22
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等級

for GC derivatization

品質等級

蒸汽密度

3.5 (vs air)

蒸汽壓力

10 mmHg ( 36 °C)
4 mmHg ( 20 °C)

化驗

≥99.0% (GC)
≥99.0%

形狀

liquid

自燃溫度

629 °F

品質

LiChropur

expl. lim.

10.3 %

反應適用性

reagent type: derivatization reagent
reaction type: Acylations

技術

gas chromatography (GC): suitable

蒸發殘留物

≤0.003%

折射率

n20/D 1.390 (lit.)

bp

138-140 °C (lit.)

mp

−73 °C (lit.)

溶解度

H2O: slightly soluble

密度

1.08 g/mL (lit.)

SMILES 字串

CC(=O)OC(C)=O

InChI

1S/C4H6O3/c1-3(5)7-4(2)6/h1-2H3

InChI 密鑰

WFDIJRYMOXRFFG-UHFFFAOYSA-N

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一般說明

乙酸酐是一种对金属有腐蚀性的酯化剂。它是一种无色液体,有强烈的醋味。它主要用于生产塑料、纤维、药物、染料和爆炸物等。
酰基化是甲硅烷基化的一种替代方法,能够通过羧酸或衍生物的作用将含由活性氢(-OH、-SH和-NH)组成的化合物转化成酯类、硫酯和酰胺。与卤化碳相邻的羰基有利于提高电子俘获检测器(ECD)响应。酰基化有几大优点:
  • 通过保护不稳定基团提高化合物的稳定性。
  • 可呈现诸如碳水化合物或氨基酸等物质的挥发性,这些物质有几个极性基团,它们不易挥发,通常在加热时分解。
  • 允许进行分离,这是未衍生化合物无法实现的。
  • 通过ECD可在极低水平上检测到化合物。

乙酸酐是一种在GC/MS分析中用于形成断裂导向衍生物的试剂。

應用

更多信息请参见产品信息
适用于乙酰、对乙酰氨基酚、乙醇、醛糖和部分甲基化醛糖、醛固酮、胺类、氨基酸、氨基糖(在多糖中)、氨基糖甲基苷、2-氨基-2-脱氧己糖、精氨酰多肽、芳基硫酸酯、胆汁酸、氨基甲酸盐、碳水化合物、脑苷酯、胱氨酸和半胱氨酸(在多肽中)、去甲基多塞平、3,4-二羟基苯基乙二醇、雌激素、多羟糖醇、吡喃己糖苷、己糖胺、异羟肟酸、羟胺、n-羟基氨基甲酸酯、羟基类固醇、纤维醇、4-甲氧基和3,4-二甲氧基苯乙胺、甲酯、甲基(甲基O-甲基-a-D-吡喃葡萄糖苷)糖醛酸酯、核苷、核苷基和糖类、部分甲基化戊糖和己糖、多肽、苯基烷基胺、苯乙胺、多糖成分、前列腺素A、B和E、血清素、唾液酸、糖类、天然糖和色胺等的衍生化。

其他說明

乙酸酐、乙酰基、n-乙酰基、n-乙酰基-n、o-乙酰基、乙酸、糖腈乙酰酯、氨基多羟糖醇乙酸、芳基乙酸、完全甲基乙酰基、甲酯、三氟乙酰基、双三甲基硅基、三甲基硅基聚氨基乙醇和O-三甲基硅基(TMS)试剂。

法律資訊

LiChropur is a trademark of Merck KGaA, Darmstadt, Germany

訊號詞

Danger

危險分類

Acute Tox. 2 Inhalation - Acute Tox. 4 Oral - Eye Dam. 1 - Flam. Liq. 3 - Skin Corr. 1B

儲存類別代碼

3 - Flammable liquids

水污染物質分類(WGK)

WGK 1

閃點(°F)

120.2 °F - closed cup

閃點(°C)

49 °C - closed cup

個人防護裝備

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter


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    1. All package sizes of this product are packaged in glass amber bottles.

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