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63176

Sigma-Aldrich

6-马来酰亚胺基己酸

≥98.0% (HPLC)

同義詞:

6-马来酰亚胺己酸, N-马来酰基-6-氨基己酸, N-(5-羧基戊基)马来酰亚胺

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About This Item

經驗公式（希爾表示法）:
C10H13NO4
CAS號碼:
55750-53-3
分子量：:
211.21
Beilstein:
1532405
MDL號碼:
MFCD00043140
分類程式碼代碼:
12352005
PubChem物質ID:
329759803
NACRES:
NA.25
暫時無法取得訂價和供貨情況

品質等級

200

化驗

≥98.0% (HPLC)

mp

86-91 °C

儲存溫度

room temp

SMILES 字串

OC(=O)CCCCCN1C(=O)C=CC1=O

InChI

1S/C10H13NO4/c12-8-5-6-9(13)11(8)7-3-1-2-4-10(14)15/h5-6H,1-4,7H2,(H,14,15)

InChI 密鑰

WOJKKJKETHYEAC-UHFFFAOYSA-N

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應用

6-马来酰亚胺基己酸可作为构建药物和其他类型生物偶联物的间隔基团。6-马来酰亚胺基己酸与 N -羟基琥珀酰亚胺酯作为双功能交联试剂使用。
用于膜蛋白中硫醇基（SH-基团）的探针。

象形圖

Exclamation mark
GHS07

訊號詞

Warning

危險聲明

H315,H335

危險分類

Skin Irrit. 2 - STOT SE 3

標靶器官

Respiratory system

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 3

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves

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分析證明 (COA)

Lot/Batch Number
BCCH4590
SLCJ2770
SLCJ2769
BCCB3944
SLBH4610

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Mitsuko Maeda et al.
Bioorganic & medicinal chemistry letters, 15(3), 621-624 (2005-01-25)
The adenovirus vector is a promising carrier for the efficient transfer of genes into cells via the coxackie-adenovirus receptor (CAR) and integrins (alphavbeta3 and alphavbeta5). The clinical use of the adenovirus vector remains problematic however. Successful administration of this vector
Shinya Kida et al.
Chemical & pharmaceutical bulletin, 55(4), 685-687 (2007-04-06)
6-maleimidohexanoic acid N-hydroxysuccinimide ester has been used widely for preparation of enzyme immunoconjugates as a unique heterobifunctional cross-linking reagent. Its heterobifunctional reactivity is good, but its ester portion hydrolyzes easily in the presence of water. Several 6-maleimidohexanoic acid active esters
Mohammed Abdelsaid et al.
Life sciences, 118(2), 268-273 (2014-01-23)
We have shown that diabetes causes cerebrovascular remodeling in part by the activation of the endothelin (ET-1) system in a glucose-dependent manner. We also reported increased yet dysfunctional cerebral angiogenesis in diabetes. Here, we tested the hypothesis that dual ET-1
Nathalie E Blachère et al.
European journal of immunology, 44(11), 3240-3251 (2014-08-12)
Paraneoplastic neurologic diseases (PND) involving immune responses directed toward intracellular antigens are poorly understood. Here, we examine immunity to the PND antigen Nova2, which is expressed exclusively in central nervous system (CNS) neurons. We hypothesized that ectopic expression of neuronal
Ralph Rahme et al.
Journal of neurosurgery, 121(6), 1354-1358 (2014-09-27)
The role of endovascular therapy in patients with acute ischemic stroke and a solitary M2 occlusion remains unclear. Through a pooled analysis of 3 interventional stroke trials, the authors sought to analyze the impact of successful early reperfusion of M2
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