USDEA Schedule II; Home Office Schedule 2; regulated under CDSA - not available from Sigma-Aldrich Canada; estupefaciente (Spain); Decreto Lei 15/93: Tabela IA (Portugal)
技術
HPLC: suitable gas chromatography (GC): suitable
應用
forensics and toxicology pharmaceutical (small molecule) veterinary
Drug and alcohol dependence, 104(3), 187-196 (2009-06-06)
G protein-coupled receptor kinases (GRKs) are a family of intracellular proteins that desensitize and regulate the responsiveness of G protein-coupled receptors (GPCRs). In the present study, we assessed the contribution of GRK6 to the regulation and responsiveness of the G
Proceedings of the National Academy of Sciences of the United States of America, 110(43), 17534-17539 (2013-10-02)
Loss-of-function mutations in the human voltage-gated sodium channel NaV1.7 result in a congenital indifference to pain. Selective inhibitors of NaV1.7 are therefore likely to be powerful analgesics for treating a broad range of pain conditions. Herein we describe the identification
The Journal of neuroscience : the official journal of the Society for Neuroscience, 33(40), 15952-15963 (2013-10-04)
The ventrolateral periaqueductal gray (vlPAG) is an integral locus for morphine action. Although it is clear that glia contribute to the development of morphine tolerance, to date, the investigation of their role has been limited to spinal and medullary loci.
Anesthesia and analgesia, 117(6), 1368-1370 (2013-11-22)
Respiratory depression can occur after neuraxial morphine administration. In the obstetric population, there are little data on respiratory depression after neuraxial morphine administration in women undergoing cesarean delivery. In this single-center, retrospective study in 5036 obstetric patients (mean body mass
Archives of disease in childhood, 98(12), 975-979 (2013-10-24)
To investigate the accuracy of morphine infusions prepared for neonates in relation to the label strength and to identify the differences in deviation between infusions made in neonatal intensive care unit (NICU) and those dispensed ready-to-use from pharmacy. Unused portions