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40252

Sigma-Aldrich

N,N-二甲基甲酰胺二乙缩醛

for esterification of fatty acids, ≥95.0% (GC)

同義詞:

1,1-二乙氧基-N,N-二甲基甲胺, 1,1-二乙氧基三甲胺

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About This Item

線性公式:
(CH3)2NCH(OC2H5)2
CAS號碼:
分子量::
147.22
Beilstein:
741889
EC號碼:
MDL號碼:
分類程式碼代碼:
12352100
PubChem物質ID:
NACRES:
NA.22

品質等級

化驗

≥95.0% (GC)

品質

for esterification of fatty acids

顏色

colorless to yellow

折射率

n20/D 1.397-1.401
n20/D 1.400 (lit.)

bp

130-133 °C (lit.)

密度

0.859 g/mL at 25 °C (lit.)

SMILES 字串

CCOC(OCC)N(C)C

InChI

1S/C7H17NO2/c1-5-9-7(8(3)4)10-6-2/h7H,5-6H2,1-4H3

InChI 密鑰

BWKAYBPLDRWMCJ-UHFFFAOYSA-N

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一般說明

N,N-Dimethylformamide diethyl acetal undergoes Me3SiCl-mediated three-component coupling reaction with alkyne to yield 2,3,4,5-tetrasubstituted pyridine derivatives.
N,N-Dimethylformamide diethyl acetal (DMF diethyl acetal) on reaction with butanol affords N,N-dimethylformamide dibutyl acetal. It participates in various alkylation, formylation, and aminomethylenation reactions. It has been synthesized from N,N-dialkyl(chloromethylene)ammonium chloride.

應用

N,N-Dimethylformamide diethyl acetal is a suitable reagent for the esterification of fatty acids. It is suitable reagent used in the quantification of cocaine and its primary metabolite, benzoyl ecgonine, from a urine matrix by gas chromatography.

其他說明

用于脂肪酸的酯化反应的试剂;综述

象形圖

Flame

訊號詞

Warning

危險聲明

防範說明

危險分類

Flam. Liq. 3

儲存類別代碼

3 - Flammable liquids

水污染物質分類(WGK)

WGK 3

閃點(°F)

82.4 °F - closed cup

閃點(°C)

28 °C - closed cup

個人防護裝備

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter


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分析證明 (COA)

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N,N-Dimethylformamide Diethyl Acetal.
Pindur U.
e-EROS Encyclopedia of Reagents for Organic Synthesis. (2001)
J.P. Thenot et al.
Analytical Letters, 217-217 (1972)
DeWolfe RH.
Carboxylic Ortho Acid Derivatives: Preparation and Synthetic Applications (Academic press), 14, 424-424 (2012)
Toshiaki Sasada et al.
The Journal of organic chemistry, 73(17), 6905-6908 (2008-07-30)
We have identified a Me3SiCl-mediated three-component coupling reaction of a functionalized enamine, N,N-dimethylformamide diethyl acetal, and an internal alkyne having an electron-withdrawing group that produces 2,3,4,5-tetrasubstituted pyridine derivatives in good to excellent yields via a single-step reaction.
N C Jain et al.
Journal of forensic sciences, 22(1), 7-16 (1977-01-01)
A gas chromatographic procedure has been developed for the simultaneous determination of cocaine and benzoyl ecgonine in urine specimens. The two drugs are extracted by isopropanol/chloroform from urine samples saturated with a bisalt buffer. The organic extract is evaporated to

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