Lipid binding constant determination kit is used for analysis of lipid binding.
成分
TRANSIL®-Ln (neutral biomembrane); 1 mL TRANSIL®-Lc (biomembrane with negative charge clusters); 1 ml each in 5 mL buffer (20 mM HEPES pH 7.0; 0.03 M NaCl) TRANSIL®-L consists of a silicate core; encased in a mobile lipid bilayer (phospholipids).
法律資訊
Transil is a registered trademark of Nimbus GmbH
儲存類別代碼
12 - Non Combustible Liquids
閃點（°F）
Not applicable
閃點（°C）
Not applicable
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分析證明 (COA)
Lot/Batch Number
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Lipid-water partitioning of 187 pharmaceuticals has been assessed with solid-supported lipid membranes (TRANSIL) in microwell plates and with multilamellar liposomes for a data comparison. The high-throughput potential of the new approach was evaluated. Drugs were incubated at pH 7.4 with
Journal of pharmaceutical sciences, 90(5), 599-606 (2001-04-05)
Quantification of membrane affinity is an important early screening step in modern drug design. However, current approaches using different lipid membrane models usually are time-consuming or show severe experimental drawbacks. In this paper we describe the use of solid-supported lipid
