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Merck
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重要文件

SCT051

Sigma-Aldrich

BioTracker Carbon Monoxide Probe 1 Live Cell Dye

Live cell imaging dye for cellular carbon monoxide (CO), a cell signalling molecule implicated in vasodilation, neurotransmission, anti-inflammatory and anti-apoptotic processes.

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About This Item

分類程式碼代碼:
12352207
NACRES:
NA.47
暫時無法取得訂價和供貨情況

形狀

lyophilized

檢測方法

fluorometric

一般說明

Carbon Monoxide (CO) is a colorless, odorless, tasteless gas that is highly toxic and lethal to mammals. However, there is growing evidence that CO can be endogenously produced in ourhuman body during the haem catabolism, and it was proved to be an important cell signaling molecule with substantial therapeutic potential protecting from vascular, inflammatory, or even cancer diseases. BioTracker Carbon Monoxide live cell dye is an allyl fluorescein ether-based probe for detecting CO in living cells. The dye is highly selective for CO and shows no effect with other analytes such as F-, Cl-, Br-, I-, AcO-, HCO3-, N3-, NO3-, SO42-, HSO4-, HSO3-, HS-, SCN-, CN-, ClO4-, IO4-, PO43-, and HPO42-, biothiols such as Cys, Hcy, and GSH, amino acids such as Ser, Trp, Ala,Phe, Gln, Glu, Lys, Leu, Gly, and Ile, and reactive oxygen/nitrogen species (ROS/RNS) such as ClO-, H2O2, NO2-, NO, HNO, ROO-, BuOO-, and -OH.
Spectral Properties:Excitation: 450- 480nm
Emission: 525 nm (Green)
Research Category:Live Cell Dye

Materials Required but Not Supplied:
  • PdCl2 (MilliporeSigma: Cat# 205885-1G or 520659-1G)
  • CROM-3 (MilliporeSigma Cat# SML0496-10mg), a carbon monoxide-releasing molecule
Important note: SCT051 staining works only in the presence of CROM-3 and PdCl2. Refer to product data sheet for more information.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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