MGAMMAG-300K

MILLIPLEX^® Mouse Immunoglobulin Isotyping Magnetic Bead Panel - Isotyping Multiplex Assay

Isotyping Bead-Based Multiplex Assays using the Luminex technology enables the simultaneous analysis of multiple immunoglobulins (Ig) in murine serum, plasma and cell culture samples.

• 同義詞: Luminex^® Mouse Isotyping Assay, Millipore Mouse Isotyping Assay, Mouse IgG, IgA, IgM immunoassay, Mouse Isotyoing Multiplex Assay
• 分類程式碼代碼: 12161503
• eCl@ss: 32161000
• NACRES: NA.84

屬性

• 品質等級: 200
• 物種活性: mouse
• 製造商／商標名: Milliplex^®
• assay range: accuracy: 100%; (IgM); accuracy: 85%; (IgG3); accuracy: 98%; (IgA); accuracy: 98%; (IgG2b); sensitivity: 0.18 ng/mL; (IgG2b); sensitivity: 0.32 ng/mL; (IgG3); sensitivity: 0.67 ng/mL; (IgG2a); sensitivity: 0.7 ng/mL; (IgG1); sensitivity: 1.1 ng/mL; (IgA); sensitivity: 1.73 ng/mL; (IgM); standard curve range: 1-900 ng/mL; (IgG2b); standard curve range: 2-1,500 ng/mL; (IgG1); standard curve range: 2-1,500 ng/mL; (IgG3); standard curve range: 2-1,500 ng/mL; (IgM); standard curve range: 3-2,000 ng/mL; (IgG2a); standard curve range: 5-3,000 ng/mL; (IgA); inter-assay cv: 14-17%; intra-assay cv: 5-10%
• 技術: multiplexing: suitable
• 檢測方法: fluorometric (Luminex xMAP)
• 運輸包裝: wet ice

描述

一般說明

Produced by plasma cells and lymphocytes, immunoglobulins (antibodies) are critically involved in immune response, attaching to antigens, and playing a role in their destruction. Immunoglobulins (Ig) can be classified by isotype, classes that differ in function and antigen response due to structure variability. Six major isotypes have been identified in placental mammals: IgM, IgG1, IgG2a, IgG2b, IgG3 and IgA – all found in normal individuals. Immunoglobulin-deficiency disorders, such as autoimmune disease, some GI conditions, and malignancies, are characterized by specific isotype deficiencies or varying concentrations of one or more isotypes. Disease states can range from the absence of one isotype class or subclass to a total deficiency of immunoglobulin classes.

MILLIPLEX^® Mouse Isotyping Bead Panel, measuring mouse IgG subclasses (1, 2a, 2b, 3), IgM, and IgA, has been designed to enable you to measure both classes and subclasses accurately – all in one well. In addition, this panel allows you to choose only those immunoglobulins you need for your experiments.

The Luminex^® xMAP^® platform uses a magnetic bead immunoassay format for ideal speed and sensitivity to quantitate multiple analytes simultaneously, dramatically improving productivity while conserving valuable sample volume.

Panel Type: Immune Response

應用

• Analytes: IgG1, IgG2a, IgG2b, IgG3, IgA, IgM
• Recommended Sample type: Serum, plasma, or tissue/cell lysate and culture supernatant
• Recommended Sample dilution: 1:50,000 diluted plasma or serum, or cell culture supernatant diluted to approximately 1μg/mL Ig well.
• Assay Run Time: One day
• Research Category: Immunology and Inflammation, Isotyping

特點和優勢

Design your multiplex kit by choosing available analytes within this panel.

聯結

Replaces: MGAM-300

法律資訊

Luminex is a registered trademark of Luminex Corp

MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany

xMAP is a registered trademark of Luminex Corp

安全資訊

• 象形圖: GHS08,GHS05,GHS07,GHS09
• 訊號詞: Danger
• 危險聲明: H302 + H312 + H332,H317,H318,H373,H411
• 防範說明: P273 - P280 - P302 + P352 + P312 - P304 + P340 + P312 - P305 + P351 + P338 - P314
• 危險分類: Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Skin Sens. 1 - STOT RE 2
• 標靶器官: Respiratory Tract
• 儲存類別代碼: 10 - Combustible liquids