MATFLAGELLIN

NEP Control Flagellin- PyroMAT^® System MAT

Non-endotoxin pyrogen control of flagellin for use in monocyte activation test

• 同義詞: NEP, NEP Control
• 分類程式碼代碼: 41116130
• eCl@ss: 32160606
• NACRES: NA.24

屬性

• 化驗: ≥95% (SDS-PAGE)
• 品質等級: 400
• 用途: sufficient for 10 tests
• 特點: Non-endotoxin pyrogen control of flagellin for use in monocyte activation test
• 製造商／商標名: PyroMAT^®
• 應用: pharmaceutical; pyrogen testing
• 相容性: configured for PyroDetect System; configured for PyroMAT^® System
• 運輸包裝: cooler
• 儲存溫度: −20°C
• 適合性: pyrogenic bacteria

描述

一般說明

The PyroMAT^® System uses cryopreserved Mono-Mac-6 (MM6) human monocytic cells as a source of monocytes. The response to a full range of pyrogens, including endotoxins and non-endotoxin pyrogens (NEPs)is determined by the measurement of interleukin-6 (IL-6) produced by the Mono-Mac-6 cells using ELISA.
NEP control flagellin is a preparation of flagellin from Salmonella typhimurium and supplied in a lyophilized form. Flagellin is a non-endotoxin pyrogen (NEP) that activates the TLR5 receptor of monocytes and can be used as a positive control with the PyroMAT^® System (Monocyte Activation Test for pyrogen detection).

特異性

TLR-5 agonist

應用

NEP control of flagellin can be used as a positive control with the PyroMAT^® System. It is to be used for Product Specific Validation (PSV) and routine testing to show that the system can detect non-endotoxin pyrogen contaminants in pharmaceutical products.

特點和優勢

Endotoxin-free product at concentration of use in MAT Purity: ≥ 95% (SDS-PAGE)

儲存和穩定性

Store unopened vials at -20°C
Do not use unopened vials after expiration date
Store resuspended aliquots at -20°C
Shelf life of aliquots can be found on the technical datasheet

法律資訊

PYROMAT is a registered trademark of Merck KGaA, Darmstadt, Germany

安全資訊

• 儲存類別代碼: 13 - Non Combustible Solids
• 水污染物質分類（WGK）: WGK 2
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable