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重要文件

MAB4619

Sigma-Aldrich

Anti-Bcl-XL Antibody, NT, clone 7D9

clone 7D9, Chemicon®, from mouse

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About This Item

分類程式碼代碼:
12352203
eCl@ss:
32160702
NACRES:
NA.41

生物源

mouse

品質等級

抗體表格

affinity purified immunoglobulin

抗體產品種類

primary antibodies

無性繁殖

7D9, monoclonal

物種活性

mouse

製造商/商標名

Chemicon®

技術

flow cytometry: suitable
immunofluorescence: suitable

同型

IgG2a

UniProt登錄號

運輸包裝

wet ice

目標翻譯後修改

unmodified

基因資訊

human ... BCL2L1(598)

一般說明

Bcl-X consists of two isoforms, Bcl-XL (long), a 241 aa protein, and Bcl-XS (short), a 178 aa protein lacking a 63-aa domain that is well conserved among members of the Bcl-2 family. Bcl-XL represses cell death, while Bcl-XS favors cell death.Bcl-X has two isoforms, Bcl-XL (long) a 241 amino acid protein and Bcl-XS (short) a 178 amino acid protein lacking a 63 amino acid domain that is well conserved among members of the Bcl-2 family. Bcl-XL represses cell death, while Bcl-XS favors cell death.

特異性

MAB4619 recognizes a protein of 27 kDa, identified as the Bcl-XL protein. Highly specific to Bcl-XL and shows no cross-reaction with Bcl-XS, Bcl-2alpha or Bax protein.

免疫原

Synthetic peptide corresponding to amino acids 35-50 (TEAPEETEAERETPSA) of mouse Bcl-XL protein. This sequence is conserved at 15 of 16 residues in rat Bcl-XL.

應用

Immunofluorescence

Flow Cytometry

Optimal working dilutions must be determined by end user.
This Anti-Bcl-XL Antibody, N-terminus, clone 7D9 is validated for use in FC, IF for the detection of Bcl-XL.

外觀

Format: Purified
Immunoglobulin purified by protein A affinity chromatography. Liquid in 10mM PBS, pH 7.4, with 0.2% BSA and 0.09% sodium azide.

其他說明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

法律資訊

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

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儲存類別代碼

12 - Non Combustible Liquids

水污染物質分類(WGK)

WGK 2

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析證明 (COA)

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Yiqing Li et al.
Proceedings of the National Academy of Sciences of the United States of America, 114(2), E209-E218 (2017-01-05)
Retinal ganglion cells (RGCs), the projection neurons of the eye, cannot regenerate their axons once the optic nerve has been injured and soon begin to die. Whereas RGC death and regenerative failure are widely viewed as being cell-autonomous or influenced

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