推薦產品
生物源
mouse
品質等級
抗體表格
purified immunoglobulin
抗體產品種類
primary antibodies
無性繁殖
4.3E8.D1, monoclonal
物種活性
mouse, rat, human
製造商／商標名
Chemicon®
技術
immunocytochemistry: suitable
immunoprecipitation (IP): suitable
同型
IgG1
NCBI登錄號
UniProt登錄號
運輸包裝
wet ice
目標翻譯後修改
unmodified
基因資訊
human ... ATP5B(506)
特異性
识别ATP合酶的β链。ATP合酶的β链是线粒体的有用亚细胞标记。
免疫原
大鼠脑线粒体
表位：β链
應用
免疫细胞化学：使用10xE6细胞或通过间接免疫荧光的粘附样品在室温下以1μ g/mL的浓度放置1小时。建议的固定剂为2-4%多聚甲醛。建议的透化方法是0.5%Triton X-100。
免疫沉淀
最佳工作稀释度必须由最终用户进行确定。
免疫沉淀
最佳工作稀释度必须由最终用户进行确定。
已发表抗ATP合酶抗体，β链，克隆4.3 E8.D1可检测ATP合酶&水平，&经验证可用于IC &IP。
研究子类别
离子通道 & 转运体
离子通道 & 转运体
研究类别
神经科学
神经科学
外觀
形式：纯化
纯化的免疫球蛋白。 0.02M磷酸盐缓冲液，0.25M NaCl和0.1%叠氮化钠的液体。
儲存和穩定性
自收到之日起，在 2-8° 以未稀释的等分试样可保存 6 个月。
其他說明
浓度：请参考批次特异性浓缩物的分析证书。
法律資訊
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
免責聲明
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
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儲存類別代碼
10 - Combustible liquids
水污染物質分類（WGK）
WGK 2
閃點（°F）
Not applicable
閃點（°C）
Not applicable
分析證明 (COA)
輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號，寫有 ‘Lot’或‘Batch’.。
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Glucose metabolism, specifically, hexokinase 2 (HK2), has a critical role in rheumatoid arthritis (RA) fibroblast-like synoviocyte (FLS) phenotype. HK2 localizes not only in the cytosol but also in the mitochondria, where it protects mitochondria against stress. We hypothesize that mitochondria-bound
Gowtham K Annarapu et al.
Redox biology, 48, 102205-102205 (2021-12-11)
Hemolysis, a pathological component of many diseases, is associated with thrombosis and vascular dysfunction. Hemolytic products, including cell-free hemoglobin and free heme directly activate platelets. However, the effect of hemolysis on platelet degranulation, a central process in not only thrombosis
Daan M Van Den Brink et al.
PLoS genetics, 14(9), e1007627-e1007627 (2018-09-11)
Increasing evidence suggests that dysregulation of lipid metabolism is associated with neurodegeneration in retinal diseases such as age-related macular degeneration and in brain disorders such as Alzheimer's and Parkinson's diseases. Lipid storage organelles (lipid droplets, LDs), accumulate in many cell
Pamela J Yao et al.
Molecular biology of the cell, 28(3), 387-395 (2016-12-10)
Mitochondria are essential organelles whose biogenesis, structure, and function are regulated by many signaling pathways. We present evidence that, in hippocampal neurons, activation of the Sonic hedgehog (Shh) signaling pathway affects multiple aspects of mitochondria. Mitochondrial mass was increased significantly
Hye-Won Hyun et al.
Frontiers in cellular neuroscience, 10, 99-99 (2016-05-06)
High mobility group box 1 (HMGB1) acts a signaling molecule regulating a wide range of inflammatory responses in extracellular space. HMGB1 also stabilizes nucleosomal structure and facilitates gene transcription. Under pathophysiological conditions, nuclear HMGB1 is immediately transported to the cytoplasm
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