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重要文件

MAB2291

Sigma-Aldrich

Anti-Integrin α3 Antibody, cytoplasmic domain, clone 54B3

clone 54B3, Chemicon®, from mouse

同義詞:

CD49c

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About This Item

分類程式碼代碼:
12352203
eCl@ss:
32160702
NACRES:
NA.41

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生物源

mouse

抗體表格

purified antibody

抗體產品種類

primary antibodies

無性繁殖

54B3, monoclonal

物種活性

human

製造商/商標名

Chemicon®

技術

immunocytochemistry: suitable
immunohistochemistry: suitable
western blot: suitable

同型

IgG1

UniProt登錄號

一般說明

Integrins are a family of heterodimeric membrane glycoproteins consisting of non-covalently associated alpha and beta subunits. More than 18 alpha and 8 beta subunits with numerous splice variant isoforms have been identified in mammals. In general, integrins function as receptors for extracellular matrix proteins. Certain integrins can also bind to soluble ligands or to counter-receptors on adjacent cells, such as the intracellular adhesion molecules (ICAMs), resulting in aggregation of cells. Signals transduced by integrins play a role in many biological processes, including cell growth, differentiation, migration and apoptosis. For integrin subunits alpha 3 and alpha 6, two cytoplasmic variants, A and B, have been identified.
MAB2291 is a mouse monoclonal generated to a synthetic peptide in the cytoplasmic domain of integrin alpha 3B.

特異性

Anti-Integrin alpha 3B recognizes the cytoplasmic domain of integrin alpha 3B. Integrin alpha 3B is present in the microvascular structures in brain and heart.

SPECIES REACTIVITIES:

Although untested, a broad species reactivity is expected due to the conserved nature of the epitope.

免疫原

Epitope: cytoplasmic domain
Synthetic peptide: CTRYYQIMPKYHAVRIREEERYPPPGSTLPTKK

應用

Research Category
Cell Structure
Research Sub Category
Integrins
This Anti-Integrin α3 Antibody, cytoplasmic domain, clone 54B3 is validated for use in WB, IC, IH for the detection of Integrin α3.
Western Blotting

Immunocytochemistry

Immunohistochemistry

Optimal working dilutions must be determined by the end user.

外觀

Format: Purified
Purified. Liquid in PBS containing 0.1% sodium azide.

儲存和穩定性

Store at 2-8°C, or in small aliquots at -20°C.

其他說明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

法律資訊

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

12 - Non Combustible Liquids

水污染物質分類(WGK)

WGK 2

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析證明 (COA)

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