MAB2058Z

Anti-Integrin β4 Antibody, clone ASC-3, azide free

clone ASC-3, Chemicon^®, from mouse

• 同義詞: CD104, MAB2058
• 分類程式碼代碼: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

屬性

• 生物源: mouse
• 品質等級: 100
• 抗體表格: purified immunoglobulin
• 抗體產品種類: primary antibodies
• 無性繁殖: ASC-3, monoclonal
• 物種活性: human
• 製造商／商標名: Chemicon^®
• 技術: flow cytometry: suitable; immunohistochemistry: suitable; immunoprecipitation (IP): suitable
• 同型: IgG1κ
• NCBI登錄號: NM_000213.3; NM_001005619.1; NM_001005731.1
• UniProt登錄號: P16144
• 運輸包裝: dry ice
• 目標翻譯後修改: unmodified
• 基因資訊: human ... ITGB4(3691)

描述

特異性

Reacts with Human beta4 integrin (CD104).

免疫原

Human squamous cell carcinoma cells (SCC9)

應用

Anti-Integrin β4 Antibody, clone ASC-3, azide free detects level of Integrin β4 & has been published & validated for use in FC, IH & IP.

Inhibition of cell attachment: inhibits SCC9 cell adhesion to human laminin and laminin GD-2 peptide, but not to EHS laminin, type IV collagen or fibronectin. Does not inhibit SKOV-3 cell adhesion to laminin, fibronectin or type IV collagen. Immunohistochemistry: on acetone-fixed frozen human epithelial tissues including tongue, foreskin and ovary. Not for use on formalin-fixed tissue. Flow cytometry: stains human squamous cell carcinoma (SCC9), ovarian carcinoma (SKOV-3) and umbilical vein endothelium (HUVEC). Stains RKO or K562 cells transfected for CD104 expression. Does not stain monocytes, neutrophils, lymphocytes, T cells, B cells or platelets. Immunoprecipitation: precipitates PAGE bands of 66, 76, 120, 135 and 200kDa (reduced) or 66, 110, 125, 130 and 190kDa (non-reduced) from surface-biotinylated SCC9 cells. Working dilutions must be determined by end user.

Research Category
Cell Structure

Research Sub Category
Integrins

外觀

Protein A purified

Format: Purified

Protein A Purified mouse immunoglobulin in 20 mM sodium phosphate, 250 mM NaCl, pH. 7.6, containing no preservatives.

儲存和穩定性

Maintain for 1 year at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

分析報告

Control
A431 cell lysate

其他說明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

法律資訊

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全資訊

• 儲存類別代碼: 12 - Non Combustible Liquids
• 水污染物質分類（WGK）: WGK 2
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable