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Merck
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AP1140

Sigma-Aldrich

Anti-GBA Mouse mAb (2E2)

liquid, clone 2E2, Calbiochem®

同義詞:

Anti-Glucosidase β, Acid

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About This Item

分類程式碼代碼:
12352203
NACRES:
NA.41

生物源

mouse

品質等級

抗體表格

purified antibody

抗體產品種類

primary antibodies

無性繁殖

2E2, monoclonal

形狀

liquid

不包含

preservative

物種活性

human

製造商/商標名

Calbiochem®

儲存條件

OK to freeze
avoid repeated freeze/thaw cycles

同型

IgG2a

運輸包裝

wet ice

儲存溫度

−20°C

目標翻譯後修改

unmodified

基因資訊

human ... GBA(2629)

一般說明

Anti-GBA, mouse monoclonal, clone 2E2, recognizes the ~60 kDa GBA in MCF-7 and HeLa cells and human breast cancer tissue. It is validated for use in ELISA, WB, ICC, and IHC on paraffin sections.
Purified mouse monoclonal antibody. Recognizes the ~60 kDa GBA protein.
Recognizes the ~60 kDa GBA protein in MCF-7 and HeLa cells and human breast cancer tissue.

免疫原

A recombinant polypeptide corresponding to amino acids of 146-236 human GBA, expressed as a GST fusion protein

警告

Toxicity: Regulatory Review (Z)

分析報告

Negative Control
293T
Positive Control
MCF-7 cells, HeLa cells, Human breast cancer tissue

其他說明

Campeau, P.M., et al. 2009. Blood114, 3181.

法律資訊

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

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儲存類別代碼

12 - Non Combustible Liquids

水污染物質分類(WGK)

nwg

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析證明 (COA)

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Laura J Smith et al.
Human molecular genetics, 32(5), 773-789 (2022-09-22)
Sequence variants or mutations in the GBA gene are numerically the most important risk factor for Parkinson disease (PD). The GBA gene encodes for the lysosomal hydrolase enzyme, glucocerebrosidase (GCase). GBA mutations often reduce GCase activity and lead to the
Ruggero Ferrazza et al.
Biochemical and biophysical research communications, 478(3), 1141-1146 (2016-08-20)
Mutations in LRRK2 gene cause inherited Parkinson's disease (PD) and variations around LRRK2 act as risk factor for disease. Similar to sporadic disease, LRRK2-linked cases show late onset and, typically, the presence of proteinaceous inclusions named Lewy bodies (LBs) in

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