ABN351

Anti-LGI3 Antibody

from rabbit, purified by affinity chromatography

• 同義詞: Leucine-rich repeat LGI family member 3, LGI1-like protein 4, Leucine-rich glioma-inactivated protein 3, LGI3
• 分類程式碼代碼: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

屬性

• 生物源: rabbit
• 品質等級: 100
• 抗體表格: affinity isolated antibody
• 抗體產品種類: primary antibodies
• 無性繁殖: polyclonal
• 純化經由: affinity chromatography
• 物種活性: human
• 技術: western blot: suitable
• UniProt登錄號: Q8N145
• 運輸包裝: wet ice
• 目標翻譯後修改: unmodified
• 基因資訊: human ... LGI3(203190)

描述

一般說明

The leucine-rich, glioma inactivated gene 3 (LGI3) is a member of the LGI family in which LGI1 is the exemplar. The LGI family consists of four of highly related proteins containing leucine-rich repeats (LRRs) which are highly similar to other transmembrane signaling molecules and receptors. LGI1 has been identified as a candidate tumor suppressor gene for glioma and plays a role in autodominant lateral temporal epilepsy (ADTLE), an epileptic syndrome characterized by focal seizures with predominant auditory symptoms. Despite its high homology with LGI1 and similar pattern of expression, mutations in LGI3 have not been found to be associated with ADTLE. LGI3 expression is induced in rat astrocyte cultures by the amyloid beta (Abeta) peptide and accumulated on neuronal plasma membranes of aged monkey brains and co-localized with Abeta.

特異性

Two isoforms of LGI3 are known to exist; this LGI3 antibody will recognize both.

免疫原

KLH-conjugated linear peptide corresponding to human LGI3.

應用

Detect the LGI3 protein using this Anti-LGI3 validated for use in WB.

品質

Evaluated by Western Blot in human brain tissue lysate.

Western Blot Analysis: 2 µg/mL of this antibody detected LGI3 in 15 µg of human brain tissue lysate.

標靶描述

~62 kDa observed

其他說明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

安全資訊

• 儲存類別代碼: 12 - Non Combustible Liquids
• 水污染物質分類（WGK）: WGK 1