跳轉至內容
Merck
全部照片(2)

文件

ABE483

Sigma-Aldrich

抗-TFAM 抗体

serum, from rabbit

同義詞:

Transcription factor A, mitochondrial, mtTFA, Testis-specific high mobility group protein, TS-HMG

登入查看組織和合約定價


About This Item

分類程式碼代碼:
12352203
eCl@ss:
32160702
NACRES:
NA.41

生物源

rabbit

品質等級

抗體表格

serum

抗體產品種類

primary antibodies

無性繁殖

polyclonal

物種活性

human, mouse, rat

技術

immunoprecipitation (IP): suitable
western blot: suitable

NCBI登錄號

UniProt登錄號

運輸包裝

wet ice

目標翻譯後修改

unmodified

基因資訊

human ... TFAM(7019)
mouse ... Tfam(21780)

一般說明

TFAM(也称mtTFA)是一种线粒体转录因子,它是线粒体转录的关键激活剂,也参与线粒体基因组复制。小鼠研究表明线粒体基因组拷贝数的调节和胚胎发育都需要该基因产物。

免疫原

His标记的重组蛋白,对应于小鼠mtTFA。

應用

使用经验证可用于蛋白质印迹&IP的该兔多克隆抗-TFAM抗体检测TFAM。
免疫沉淀分析:一个来自独立实验室的代表性批次使C2C12细胞裂解液做工的Chd2免疫沉淀(Harada,A.,et al.(2012).
研究子类别
转录因子
研究类别
表观遗传学&核功能

品質

通过蛋白质印迹法在C2C12 细胞裂解物中进行评价。

蛋白质印迹分析:该抗体的1:1,000 稀释液在10 µg C2C12细胞裂解液中检测到TFAM。

標靶描述

观测值〜27 kDa

外觀

兔多克隆抗血清,含0.05%叠氮化钠。
未纯化

儲存和穩定性

自收到之日起在-20°C可稳定保存1年。
使用建议:收货后,在取下瓶盖之前,将小瓶离心并轻轻混合溶液。分装到微量离心管中,并储存于-20°C。避免反复冻融循环,以免损坏IgG和影响产品性能。

免責聲明

除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。

Not finding the right product?  

Try our 產品選擇工具.

儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 1


分析證明 (COA)

輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號,寫有 ‘Lot’或‘Batch’.。

已經擁有該產品?

您可以在文件庫中找到最近購買的產品相關文件。

存取文件庫

Jong-Hyuk Lee et al.
Experimental & molecular medicine, 54(12), 2135-2147 (2022-12-07)
PARPs play fundamental roles in multiple DNA damage recognition and repair pathways. Persistent nuclear PARP activation causes cellular NAD+ depletion and exacerbates cellular aging. However, very little is known about mitochondrial PARP (mtPARP) and poly ADP-ribosylation (PARylation). The existence of
Nicole DeFoor et al.
Scientific reports, 13(1), 15339-15339 (2023-09-16)
SARS-CoV-2 causes the severe respiratory disease COVID-19. Remdesivir (RDV) was the first fast-tracked FDA approved treatment drug for COVID-19. RDV acts as an antiviral ribonucleoside (adenosine) analogue that becomes active once it accumulates intracellularly. It then diffuses into the host
Krishna Prahlad Maremanda et al.
Toxicology and applied pharmacology, 385, 114788-114788 (2019-11-05)
Cigarette smoke (CS)-induced lung inflammation and Chronic Obstructive Pulmonary disease (COPD) involves mitochondrial dysfunction. Mesenchymal stem cells (MSC) and MSC-derived exosomes (EXO) are reported to show therapeutic effects in many animal models of inflammation and injury. In the present study
Wenci Weng et al.
Experimental and therapeutic medicine, 23(3), 239-239 (2022-03-01)
Type 1 diabetes (T1D) is characterized by dysregulated blood glucose and liver metabolism. In previous studies, niclosamide ethanolamine salt (NEN) and artemether (Art) displayed significant hypoglycemic effects. However, their combined therapeutic effects on the liver in T1D have remained elusive.
Sylvia Torres-Odio et al.
Journal of immunology (Baltimore, Md. : 1950), 206(8), 1890-1900 (2021-03-19)
Caseinolytic mitochondrial matrix peptidase proteolytic subunit (CLPP) is a serine protease that degrades damaged or misfolded mitochondrial proteins. CLPP-null mice exhibit growth retardation, deafness, and sterility, resembling human Perrault syndrome, but also display immune system alterations. However, the molecular mechanisms

我們的科學家團隊在所有研究領域都有豐富的經驗,包括生命科學、材料科學、化學合成、色譜、分析等.

聯絡技術服務