ABC107

Anti-KIF3A Antibody

from rabbit, purified by affinity chromatography

• 同義詞: Kinesin-like protein KIF3A, Microtubule plus end-directed kinesin motor 3A
• 分類程式碼代碼: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

屬性

• 生物源: rabbit
• 抗體表格: affinity isolated antibody
• 抗體產品種類: primary antibodies
• 無性繁殖: polyclonal
• 純化經由: affinity chromatography
• 物種活性: human
• 物種活性（以同源性預測）: baboon (based on 100% sequence homology), bovine (based on 100% sequence homology), chimpanzee (based on 100% sequence homology)
• 技術: immunocytochemistry: suitable
• NCBI登錄號: NP_008985
• UniProt登錄號: Q9Y496
• 運輸包裝: wet ice
• 目標翻譯後修改: unmodified
• 基因資訊: human ... KIF3A(11127)

描述

一般說明

Kinesin-like protein KIF3 (KIF3A) is a member of the heteromeric family of kinesins and plays an important role in primary cilia formation. KIF3A functions as a microtubule-based anterograde translocator for membranous organelles and forms a heterotrimeric KIF3 complex with KIF3B or KIF3C and an associated protein, KAP3. Mutations in in KIF3A have been associated with cranial base growth retardation and dysmorphogenesis.

特異性

Other homologies: Mouse, Rat, Chicken, Zebrafish, and Frog (92% sequence homology).

免疫原

KLH-conjugated linear peptide corresponding to human KIF3A.

應用

Immunocytochemistry Analysis: A 1:500 dilution from a representative lot detected KIF3A in A431, HeLa, and NIH/3T3 cells.

Research Category
Apoptosis & Cancer

Research Sub Category
Apoptosis - Additional

This Anti-KIF3A Antibody is validated for use in ICC for the detection of KIF3A.

品質

Evaluated by Western Blot in SH-SY5Y cell lysate.

Western Blot Analysis: 1 µg/mL of this antibody detected KIF3A in 10 µg of SH-SY5Y cell lysate.

標靶描述

~80 kDa observed

外觀

Affinity purified

Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

儲存和穩定性

Stable for 1 year at 2-8°C from date of receipt.

分析報告

Control
SH-SY5Y cell lysate

其他說明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全資訊

• 儲存類別代碼: 12 - Non Combustible Liquids
• 水污染物質分類（WGK）: WGK 1
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable