AB3040

Anti-Uncoupling Protein 2 Antibody

Chemicon^®, from rabbit

• 同義詞: UCP2
• 分類程式碼代碼: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

屬性

• 生物源: rabbit
• 品質等級: 100
• 抗體表格: affinity purified immunoglobulin
• 抗體產品種類: primary antibodies
• 無性繁殖: polyclonal
• 純化經由: affinity chromatography
• 物種活性: mouse
• 製造商／商標名: Chemicon^®
• 技術: ELISA: suitable; western blot: suitable
• NCBI登錄號: NM_003355.2
• UniProt登錄號: P55851
• 運輸包裝: dry ice
• 目標翻譯後修改: unmodified
• 基因資訊: mouse ... Ucp2(22228)

描述

特異性

Uncoupling Protein 2 (UCP2), mouse. Mouse UCP2 is a 309 amino acid mitochondrial uncoupling protein (Fleury et al. 1997). It is only 59% homologous with UCP1 found in brown adipose tissues. Mouse UCP2 (chromosome 7) has approximately 95% homology with human UCP2 located on chromosome 11 (Fleury et al. 1997). UCP2 has wide tissue distribution in mouse tissues (brain, kidney, liver, brown adipose tissue, heart, and muscle). UCP2 may play a critical role in energy balance, body weight, and thermoregulation (Fleury et al. 1997; Flier & Lowell 1997).

SPECIES REACTIVITIES: The antibody has not yet been tested for cross-reactivity to other species. The sequence used for immunization shows 100% homology in rat, 86% homology in human, porcine, canine and bovine.

免疫原

14 aa peptide sequence near the C-terminus of the mouse UCP2 (Fleury et al. 1997). The peptide has no significant homology with UCP1 or UCP3 (Boss et al. 1997). This peptide is available for blocking as catalog number AG788.

應用

Anti-Uncoupling Protein 2 Antibody is an antibody against Uncoupling Protein 2 for use in ELISA & WB.

Research Category
Metabolism

Research Sub Category
Ion & Transport Channels

Western Blotting: 1-10 μg/mL using Chemiluminescence technique.

ELISA: 1:10,000-1:100,000; using 50-100 ng UCP2 control peptide/well.

Optimal working dilutions must be determined by end user.

外觀

Affinity purified immunoglobulin. Liquid in PBS, pH 7.4 with 0.1% BSA as stabilizer and 0.02% sodium merthiolate.

儲存和穩定性

Maintain at -20°C in undiluted aliquots for up to 12 months. Avoid repeated freeze/thaw cycles.

法律資訊

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全資訊

• 儲存類別代碼: 12 - Non Combustible Liquids
• 水污染物質分類（WGK）: WGK 2
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable