AB15518

Anti-Neuronal pentraxin 1 Antibody

Chemicon^®, from rabbit

• 同義詞: NPX1
• 分類程式碼代碼: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

屬性

• 生物源: rabbit
• 品質等級: 100
• 抗體表格: affinity purified immunoglobulin
• 抗體產品種類: primary antibodies
• 無性繁殖: polyclonal
• 純化經由: affinity chromatography
• 物種活性: mouse
• 製造商／商標名: Chemicon^®
• 技術: ELISA: suitable; immunohistochemistry: suitable; western blot: suitable
• NCBI登錄號: NM_002522.2
• UniProt登錄號: Q15818
• 運輸包裝: dry ice
• 目標翻譯後修改: unmodified
• 基因資訊: human ... NPTX1(4884)

描述

一般說明

Neuronal Pentraxins: A new family of putative integral membrane pentraxins or Neuronal pentraxins identified through interaction with a presynaptic snake venom toxin taipoxin. NPX1, NPX2 and NPXR (Neuronal Pentraxin Receptor), the three neuronal pentraxins represent a novel neuronal uptake pathway that may function during synapse formation and remodeling. The N-terminal half of neuronal pentraxins are 20-30% identical to previously identified pentraxins (CRP and SAP), the three neuronal pentraxins are 50% identical to each other and are significantly larger than the classical pentraxins (>50 versus 30kDa), suggesting that they may have additional novel functions. NPX1(Neuronal Pentraxin 1) a 432aa protein in mouse and rat, 430aa in human (chr 17q25). It mediates the uptake of degraded synaptic material which could play an important role in synaptic remodeling, expressed in brain.

特異性

Neuronal pentraxin 1 (NPX1).

The immunogen sequence is 94% conserved in rat, and 82% in human NPX1.

免疫原

Synthetic peptide near the N-terminus of mouse NPX1

應用

Research Category
Neuroscience

Research Sub Category
Synapse & Synaptic Biology

This Anti-Neuronal pentraxin 1 Antibody is validated for use in ELISA, WB, IH for the detection of Neuronal pentraxin 1.

Western blot: 1-10 µg/mL using ECL.
Immunohistochemistry: Not tested. It is recommended that the antibody be tried at 2-20 µg/mL
ELISA: 0.5-1 µg/mL using control peptide.
Optimal working dilutions must be determined by end user.

外觀

ImmunoAffinity Purified

Liquid in PBS with 0.1% BSA.

儲存和穩定性

Maintain at -20°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles.

法律資訊

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全資訊

• 儲存類別代碼: 10 - Combustible liquids
• 水污染物質分類（WGK）: WGK 2
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable