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8.55131

Sigma-Aldrich

Dawson Dbz AM resin (100-200 mesh)

3-(Fmoc-amino)-4-aminobenzoyl AM resin (100-200 mesh) Novabiochem®

同義詞:

3-(Fmoc-amino)-4-aminobenzoyl Rink Amide AM resin (100 - 200 mesh), Dawson Nbz AM resin (100-200 mesh)

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About This Item

分類程式碼代碼:
13111023
NACRES:
NA.22
暫時無法取得訂價和供貨情況

品質等級

200

產品線

Novabiochem®

形狀

beads

反應適用性

reaction type: Fmoc solid-phase peptide synthesis

製造商／商標名

Novabiochem®

應用

peptide synthesis

官能基

amine

儲存溫度

2-8°C

相關類別

一般說明

A novel safety-catch resin for preparation peptide thioesters by Fmoc SPPS. Linker is activated to cleavage by thiols by treatment with CDI.

Associated Protocols and Technical Articles
Protocols for Loading of Peptide Synthesis Resins

分析報告

Color (visual): light yellow to yellow to brown
Appearance of substance (visual): beads
Loading (photometric determination of the Fmoc-chromophore liberated upon treatment with piperidine/DMF.): 0.40 - 0.80 mmol/g
Swelling Volume (in DMF): lot specific result
Swelling Volume (in CH₂Cl₂): lot specific result
Total swelling volume acc. Houben Weyl (in CH2Cl2): ≥ 5.2 ml/g
Total swelling volume acc. Houben Weyl (in DMF): ≥ 5.2 ml/g
100 - 200 mesh

法律資訊

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 3

閃點（°F）

Not applicable

閃點（°C）

Not applicable

分析證明 (COA)

輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號，寫有 ‘Lot’或‘Batch’.。

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文章

Fmoc SPPS Linkers

Novabiochem® offers a wide range of linkers and derivatized resins for Fmoc solid-phase peptide synthesis with specialized protocols.

條款

多肽樹脂載入步驟

檢視各種樹脂，如 Merrifield、三羥基樹脂及羥甲基官能化樹脂，用於固定多肽以達到各種不同的應用。

Peptide Resin Loading Protocols

Review various resins like Merrifield, trityl-based, and hydroxymethyl-functionalized for peptide immobilization for diverse applications.

Questions

  1. Hi. I need a resin for my synthesis where I can deprotect both Fmoc and Boc without cleaving the peptide from the resin. Is this resin suitable for this application? or do you have any suitable safety catch resin? Many thanks.

    1 answer

    1. Unfortunately, this material is not tested for suitability for any specific application. However, a brief search of the literature suggests that it may not be compatible for Boc peptides. Please see the links below to review Fmoc and Boc resin cleavage and protection information and products that may be helpful.

      Fmoc Resin Cleavage and Deprotection:
      https://www.sigmaaldrich.com/technical-documents/technical-article/chemistry-and-synthesis/peptide-synthesis/fmoc-cleavage-deprotection

      Boc Resin Cleavage and Deprotection
      https://www.sigmaaldrich.com/technical-documents/technical-article/chemistry-and-synthesis/peptide-synthesis/boc-resin-cleavage

      Please see the link below to review an additional publication that may be helpful:
      https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11012524/

      Helpful?

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