8.55061

HMPB-MBHA resin

Novabiochem^®

• 同義詞: 4-Hydroxymethyl-3-methoxyphenoxybutyric acid MBHA resin
• 分類程式碼代碼: 13111023
• NACRES: NA.22

屬性

• 品質等級: 200
• 產品線: Novabiochem^®
• 形狀: beads
• 反應適用性: reaction type: Fmoc solid-phase peptide synthesis
• 製造商／商標名: Novabiochem^®
• 應用: peptide synthesis
• 官能基: alcohol
• 儲存溫度: 2-30°C

描述

一般說明

This support consists of MBHA resin functionalized with Riniker′s hyperacid-labile 4-hydroxymethyl-3-methoxyphenoxybutyric acid linker ^[1].This hyperacid-sensitive resin is a useful tool for the Fmoc SPPS of protected peptide acid fragments. Attachment of carboxylic acids is normally achieved by DMAP catalyzed esterification with the appropriate symmetrical anhydride, or by using 2,6-dichlorobenzoylchloride/pyridine ^[2] or MSNT/Melm activation ^[3,4,5].Detachment of these functionalities can be effected by treatment with 1-5% TFA in DCM.

Associated Protocols and Technical Articles
Protocols for Loading of Peptide Synthesis Resins

聯結

Replaces: 01-64-0036

分析報告

Colour (visual): white to yellow to beige
Appearance of substance (visual): beads
Loading (determined from the substitution of the Fmoc-Leu loaded resin): 0.40 - 1.00 mmol/g
Swelling Volume (in DMF): lot specific result
The polymer matrix is copoly ( styrene - 1% DVB ) 100- 200 mesh

法律資訊

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

安全資訊

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 1
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable