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重要文件

8.52208

Sigma-Aldrich

Fmoc-3,4-dehydro-Pro-OH

Novabiochem®

同義詞:

Fmoc-3,4-dehydro-Pro-OH, N-α-Fmoc-3,4-dehydro-L-proline

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About This Item

經驗公式(希爾表示法):
C20H17NO4
CAS號碼:
分子量::
335.35
MDL號碼:
分類程式碼代碼:
12352209
NACRES:
NA.22
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品質等級

產品線

Novabiochem®

化驗

≥85.0% (acidimetric)
≥98% (TLC)
≥98.0% (HPLC)

形狀

powder

反應適用性

reaction type: Fmoc solid-phase peptide synthesis

製造商/商標名

Novabiochem®

應用

peptide synthesis

官能基

Fmoc

儲存溫度

15-25°C

SMILES 字串

N4([C@@H](C=CC4)C(=O)O)C(=O)OCC1c2c(cccc2)c3c1cccc3

InChI

1S/C20H17NO4/c22-19(23)18-10-5-11-21(18)20(24)25-12-17-15-8-3-1-6-13(15)14-7-2-4-9-16(14)17/h1-10,17-18H,11-12H2,(H,22,23)/t18-/m0/s1

InChI 密鑰

OALUMAMYGOBVTF-SFHVURJKSA-N

一般說明

Standard building block for introduction of dehydroproline residues by Fmoc SPPS.

Associated Protocols and Technical Articles
Cleavage and Deprotection Protocols for Fmoc SPPS

聯結

Replaces: 04-12-1051

分析報告

Color (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Enantiomeric purity: ≥ 97.0 % (a/a)
Purity (TLC(011A)): ≥ 98 %
Purity (TLC(0811)): ≥ 98 %
Assay (HPLC, area%): ≥ 98.0 % (a/a)
Solubility (1 mmole in 2 ml DMF): clearly soluble
Assay (acidimetric): ≥ 85.0 %
Water (K. F.): ≤ 5.0 %

To see the solvent systems used for TLC of Novabiochem® products please click here.

法律資訊

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 2

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析證明 (COA)

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脯氨酸類似物是調節天然存在以及全新設計的線性和環狀多肽的生物、藥物或物理化學特性的理想候選物。

Proline analogues are promising candidates for tuning the biological, pharmaceutical, or physicochemical properties of naturally occuring, as well as de novo designed, linear, and, cyclic peptides.

Unnatural amino acids, the non-proteinogenic amino acids that either occur naturally or are chemically synthesized, are becoming more and more important as tools for modern drug discovery research.

非天然胺基酸,也就是天然存在或化學合成的非蛋白質胺基酸,作為現代藥物發現研究的工具,正變得越來越重要。

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