537011
Prolyl Endopeptidase Inhibitor II
The Prolyl Endopeptidase Inhibitor II, also referenced under CAS 108708-25-4, controls the biological activity of Prolyl Endopeptidase. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.
同義詞:
Prolyl Endopeptidase Inhibitor II, Z-PP-CHO
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About This Item
暫時無法取得訂價和供貨情況
推薦產品
品質等級
化驗
≥97% (HPLC)
形狀
oil
製造商／商標名
Calbiochem®
儲存條件
OK to freeze
protect from light
顏色
colorless to off-white
溶解度
DMSO: 10 mg/mL
DMF: soluble
ethyl acetate: soluble
運輸包裝
ambient
儲存溫度
−20°C
一般說明
A cell-permeable dipeptide aldehyde that acts as a specific, potent, slow and tight-binding transition state analog inhibitor of prolyl endopeptidase (Ki = 350 pM and 500 pM for mouse brain and human brain prolyl endopeptidase, respectively). Reported to form a hemiacetal with the active-site serine.
生化／生理作用
Cell permeable: yes
Primary Target
Mouse brain prolylendooeotidase
Mouse brain prolylendooeotidase
Product does not compete with ATP.
Reversible: no
Target Ki: 350 pM and 500 pM for mouse brain and human brain prolyl endopeptidase, respectively
包裝
Packaged under inert gas
警告
Toxicity: Standard Handling (A)
序列
Z-Pro-Pro-CHO
重構
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
其他說明
Fülöp, V., et al. 1998. Cell94, 161.
Kahyaoglu, A., et al. 1997. Biochem. J.322, 839.
Bakker, A.V., et al. 1990. Biochem. J.271, 559.
Wilk, S., and Orlowski, M. 1983. J. Neurochem.41, 69.
Kahyaoglu, A., et al. 1997. Biochem. J.322, 839.
Bakker, A.V., et al. 1990. Biochem. J.271, 559.
Wilk, S., and Orlowski, M. 1983. J. Neurochem.41, 69.
法律資訊
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
儲存類別代碼
10 - Combustible liquids
水污染物質分類（WGK）
WGK 1
閃點（°F）
Not applicable
閃點（°C）
Not applicable
分析證明 (COA)
輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號，寫有 ‘Lot’或‘Batch’.。
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Biomedicines, 10(6) (2022-06-25)
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Neural regeneration research, 19(2), 434-439 (2023-07-25)
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Nature communications, 12(1), 2673-2673 (2021-05-13)
Vesicular traffic and membrane contact sites between organelles enable the exchange of proteins, lipids, and metabolites. Recruitment of tethers to contact sites between the endoplasmic reticulum (ER) and the plasma membrane is often triggered by calcium. Here we reveal a
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