5310-OP

HEPES

>= 99%, Free Acid, fine powder, OmniPur^® Grade

• 同義詞: HEPES, N-2-羟乙基哌嗪乙烷磺酸-N′-2-乙磺酸, 4-（2-羟乙基）哌嗪-1-乙磺酸, N-（2-羟乙基）哌嗪-N′-（2-乙磺酸）
• 經驗公式（希爾表示法）: C₈H₁₈N₂O₄S
• CAS號碼: 7365-45-9
• 分子量：: 238.30
• Beilstein: 883043
• MDL號碼: MFCD00006158
• 分類程式碼代碼: 12352207
• NACRES: NA.21

屬性

• product name: HEPES, OmniPur^® Grade, >= 99%, Free Acid
• 品質等級: 100
• 形狀: fine powder
• 製造商／商標名: Calbiochem^®
• 儲存條件: OK to freeze
• 顏色: white
• 有用的pH值範圍: 6.8-8.2
• pKa (25 °C): 7.5
• 運輸包裝: ambient
• 儲存溫度: 10-30°C
• SMILES 字串: OCCN1CCN(CC1)CCS(O)(=O)=O
• InChI: 1S/C8H18N2O4S/c11-7-5-9-1-3-10(4-2-9)6-8-15(12,13)14/h11H,1-8H2,(H,12,13,14)
• InChI 密鑰: JKMHFZQWWAIEOD-UHFFFAOYSA-N

描述

一般說明

分子生物学

A₂₆₀组（0.1 M，水）：≤0.05 AU
A₂₈₀（0.1 M，水）：≤0.05 AU
纯度（基于干燥基）：≥99
DNase：未检出
重金属（以Pb计）：≤0.001%
磷酸酶：未检出
pKa@25°C：6.80-8.20
蛋白酶：未检出
RNA酶：未检出





仅供实验室和制造使用。不得用于药物、食物或家庭用途。

應用

<ul>
<li><strong>Phenothiazine appended thiophene derivative: a trilateral approach to copper ion detection in living cells and aqueous samples.</strong>: This study explores the use of HEPES buffer in the detection of copper ions, showcasing its utility in maintaining the stability of the sensor in aqueous solutions and live cell environments. The findings indicate that HEPES buffer plays a crucial role in the accuracy and efficiency of ion detection assays, which is essential for biochemists working with metal ion sensors (Ilakiyalakshmi et al., 2024).</li>
<li><strong>Evaluation of acute intravenous toxicity of HEPES: Is Good′s buffer good and safe enough for clinical utilization in nuclear medicine </strong>: This research assesses the safety of HEPES buffer for intravenous use, specifically its acute toxicity. The results are vital for biochemists in nuclear medicine, indicating that HEPES is a safe and effective buffering agent for clinical applications (Guleria et al., 2024).</li>
<li><strong>Nanoscale engineering of gold nanostars for enhanced photoacoustic imaging.</strong>: The study highlights the use of HEPES buffer in the synthesis of gold nanostars, which significantly improves photoacoustic imaging. This demonstrates the buffer′s importance in nanobiotechnology, particularly in enhancing the stability and functionality of nanomaterials used in imaging techniques (Zhang et al., 2024).</li>
<li><strong>Influx of zwitterionic buffer after intracytoplasmic sperm injection (ICSI) membrane piercing alters the transcriptome of human oocytes.</strong>: This article discusses how HEPES buffer influences the transcriptome of human oocytes post-ICSI, highlighting its role in reproductive biology and assisted reproductive technologies. The findings are crucial for biochemists focusing on fertility treatments and genetic studies (Mendola et al., 2024).</li>
<li><strong>One Method to Label Them All": A Single Fully Automated Protocol for GMP-Compliant 68Ga Radiolabeling of PSMA-11, Transposable to PSMA-I and PSMA-617.</strong>: This paper outlines a protocol using HEPES buffer for radiolabeling in nuclear medicine, emphasizing its application in producing radiopharmaceuticals. The research supports the buffer′s critical role in maintaining the quality and compliance of radiolabeling processes (Fouillet et al., 2024).</li>
</ul>

法律資訊

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

OMNIPUR is a registered trademark of Merck KGaA, Darmstadt, Germany

安全資訊

• 儲存類別代碼: 13 - Non Combustible Solids
• 水污染物質分類（WGK）: WGK 1
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable