5.04840

(R)-CPPene

• 同義詞: (R)-CPPene, (R)-4-[(2E)-3-Phosphono-2-propenyl]-2-piperazinecarboxylic acid, SDZ EAA 494, Midafotel
• 經驗公式（希爾表示法）: C₈H₁₅N₂O₅P
• CAS號碼: 117414-74-1
• 分子量：: 250.19
• 分類程式碼代碼: 12352200
• NACRES: NA.77

屬性

• 化驗: ≥99% (HPLC)
• 品質等級: 100
• 形狀: solid
• 製造商／商標名: Calbiochem^®
• 儲存條件: OK to freeze; protect from light
• 顏色: white
• 溶解度: H₂O: 100 mM
• 儲存溫度: 2-8°C
• InChI: 1S/C8H15N2O5P/c11-8(12)7-6-10(4-2-9-7)3-1-5-16(13,14)15/h1,5,7,9H,2-4,6H2,(H,11,12)(H2,13,14,15)/b5-1+/t7-/m1/s1
• InChI 密鑰: VZXMZMJSGLFKQI-ABVWVHJUSA-N

描述

一般說明

A highly potent competitive antagonist of NMDA receptors (ED₅₀ = 39 nM; pA2 = 6.8). Biologically active admitted systemically. Frequently used in assessing the functional roles of NMDA receptors mediated neurotransmissions in a variety of research areas, such as excitotoxic cell death, apoptosis, bipolar disorders, ischemia, traumatic brain injury, epilepsy, and neuropathic pain.

生化／生理作用

Primary Target
NMDA receptors

警告

Toxicity: Standard Handling (A)

重構

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

其他說明

Lowe, D., et al. 1990. Neurosci. Lett.113, 315.
Bullock, R., et al. 1990. Stroke.21, 32.
Bespalov, A., et al. 1998. Eur. J. Pharmacol.351, 299.

Lowe, D., et al. 1994. Neurochem. Inter.25, 583.
Duty, S. 2012. CNS Drugs26, 1017.

法律資訊

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

安全資訊

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable