跳轉至內容
Merck
全部照片(1)

重要文件

407952

Sigma-Aldrich

离子霉素钙盐,来源于链霉菌

Ionomycin, Calcium Salt, Streptomyces conglobatus, CAS 56092-82-1, is useful in cell activation experiments when calcium dose-response data are not required.

同義詞:

离子霉素钙盐,来源于链霉菌

登入查看組織和合約定價


About This Item

經驗公式(希爾表示法):
C41H70O9 · Ca
CAS號碼:
分子量::
747.07
MDL號碼:
分類程式碼代碼:
12352200

品質等級

化驗

≥97% (HPLC)

形狀

solid

製造商/商標名

Calbiochem®

儲存條件

OK to freeze
protect from light

顏色

white to off-white

溶解度

DMSO: 100 mg/mL

運輸包裝

ambient

儲存溫度

2-8°C

InChI

1S/C41H71O9.Ca/c1-25(21-29(5)34(43)24-35(44)30(6)22-27(3)20-26(2)14-15-38(46)47)12-11-13-28(4)39(48)31(7)36(45)23-33-16-18-41(10,49-33)37-17-19-40(9,50-37)32(8)42;/h11,13,24-33,36-37,39,42,45,48H,12,14-23H2,1-10H3,(H,46,47);/q-1;+2/p-1/b13-11+;/t25-,26-,27+,28-,29-,30+,31+,32-,33+,36+,37-,39-,40+,41+;/m1./s1

InChI 密鑰

RULWQOBWZOQCOY-SQNLDGQHSA-M

一般說明

pH 7-9.5条件下与Ca2+的配合物,具有强烈的紫外吸收。与A23187相比,它没有荧光。有助于研究Ca2+的跨生物膜转运。诱导胚胎皮层神经元凋亡性变性。同时诱导成熟的Burkitt淋巴瘤细胞系发生G1期细胞周期阻滞。通常用于不需要钙剂量反应数据的细胞活化实验。
可用于不需要钙剂量反应数据的细胞活化实验。也可以10 mM的DMSO溶液(货号407953)提供。

生化/生理作用

主要目的
可用于细胞活化实验
产品不与ATP竞争。
可逆:否
细胞渗透性:否

包裝

用惰性气体包装

警告

毒性:有害(C)

其他說明

Dupuy d′Angeac, A., et al. 1993.J. Cell Physiol.154, 44.
Lee, H.C.1993.J. Biol. Chem.268, 293.

法律資訊

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

象形圖

Exclamation mark

訊號詞

Warning

危險聲明

危險分類

Acute Tox. 4 Oral

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析證明 (COA)

輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號,寫有 ‘Lot’或‘Batch’.。

已經擁有該產品?

您可以在文件庫中找到最近購買的產品相關文件。

存取文件庫

Diana P Saraiva et al.
Frontiers in oncology, 10, 1543-1543 (2020-09-26)
3D cell culture including different cell types, such as immune cells, is a representative platform that mimics the tumor microenvironment. Here we disclose an easy-to-handle 3D co-culture protocol using a scaffold-free technique with the breast cancer cell line MDA-MB-231 and
Jinfeng Cai et al.
eLife, 10 (2021-04-10)
The major barrier to curing HIV-1 infection is a small pool of latently infected cells that harbor replication-competent viruses, which are widely considered the origin of viral rebound when antiretroviral therapy (ART) is interrupted. The difficulty in distinguishing latently infected cells
Alfredo J Hernandez et al.
Proceedings of the National Academy of Sciences of the United States of America, 117(1), 415-425 (2019-12-25)
Transposable elements make up half of the mammalian genome. One of the most abundant is the short interspersed nuclear element (SINE). Among their million copies, B2 accounts for ∼350,000 in the mouse genome and has garnered special interest because of
Yojet Sharma et al.
Wellcome open research, 5, 16-16 (2020-03-21)
The development of the human brain involves multiple cellular processes including cell division, migration, and dendritic growth. These processes are triggered by developmental cues and lead to interactions of neurons and glial cells to derive the final complex organization of
Maria E Moreno-Fernandez et al.
STAR protocols, 2(4), 100937-100937 (2021-11-16)
Isolation of viable immune cells from human tissues is critical for the characterization of cellular and molecular processes underlying disease pathogenesis. Here, we describe protocols for the isolation of highly viable immune cells from liver wedges and mesenteric white adipose

我們的科學家團隊在所有研究領域都有豐富的經驗,包括生命科學、材料科學、化學合成、色譜、分析等.

聯絡技術服務