推薦產品
產品名稱
Erastin, A cell-permeable piperazinyl-quinazolinone compound that exhibits oncogene-selective lethality.
品質等級
化驗
≥98% (HPLC)
形狀
solid
製造商/商標名
Calbiochem®
儲存條件
OK to freeze
protect from light
顏色
white
溶解度
DMSO: 50 mg/mL
運輸包裝
wet ice
儲存溫度
−20°C
SMILES 字串
Clc1ccc(cc1)OCC(=O)N2CCN(CC2)C(C)c3[n]([c](c5c(n3)cccc5)=O)c4c(cccc4)OCC
InChI
1S/C30H31ClN4O4/c1-3-38-27-11-7-6-10-26(27)35-29(32-25-9-5-4-8-24(25)30(35)37)21(2)33-16-18-34(19-17-33)28(36)20-39-23-14-12-22(31)13-15-23/h4-15,21H,3,16-20H2,1-2H3
InChI 密鑰
BKQFRNYHFIQEKN-UHFFFAOYSA-N
一般說明
具有致癌基因选择性杀伤力的细胞可渗透的哌嗪基-喹唑啉酮化合物。显示结合线粒体电压依赖性阴离子通道(VDAC)并改变其门控;在几种人类肿瘤中快速诱导氧化性,非凋亡性细胞死亡,这些肿瘤在RAS-RAF-MEK信号传导中具有激活突变(在BJ-TERT/LT/ST/RASV12细胞中EC50 = 6.0 µM)。
包裝
用惰性气体包装
警告
毒性:标准处理(A)
重構
复溶后,等分并冷冻保存(-20°C)。储备溶液在-20°C下可稳定保存至多6个月。
其他說明
Yagoda, N., et al. 2007.Nature447, 864.
法律資訊
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
儲存類別代碼
11 - Combustible Solids
水污染物質分類(WGK)
WGK 3
閃點(°F)
Not applicable
閃點(°C)
Not applicable
分析證明 (COA)
輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號,寫有 ‘Lot’或‘Batch’.。
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