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324626

Millipore

乙二醇双(2-氨基乙基醚)四乙酸,分子生物学级

EGTA, Molecular Biology Grade

同義詞:

乙二醇双(2-氨基乙基醚)四乙酸,分子生物学级

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About This Item

經驗公式(希爾表示法):
C14H24N2O10
CAS號碼:
分子量::
380.35
MDL號碼:
分類程式碼代碼:
12352106
NACRES:
NA.25
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等級

Molecular Biology

品質等級

描述

RTECS - AH3760000

化驗

≥98% dry basis (complexometric)

形狀

solid (fine)

反應適用性

reagent type: chelator

製造商/商標名

Calbiochem®

儲存條件

OK to freeze

顏色

white

溶解度

1 M NaOH: soluble

正離子痕跡

heavy metals (as Pb): ≤0.001%

異物活動

DNases, proteases, RNases, none detected

運輸包裝

ambient

儲存溫度

10-30°C

SMILES 字串

N(CCOCCOCCN(CC(=O)O)CC(=O)O)(CC(=O)O)CC(=O)O

InChI

1S/C14H24N2O10/c17-11(18)7-15(8-12(19)20)1-3-25-5-6-26-4-2-16(9-13(21)22)10-14(23)24/h1-10H2,(H,17,18)(H,19,20)(H,21,22)(H,23,24)

InChI 密鑰

DEFVIWRASFVYLL-UHFFFAOYSA-N

一般說明

对Ca2+有选择性的螯合剂。每个分子结合一个阳离子。诱导嗜铬细胞瘤(PC12)细胞发生凋亡。

應用


  • Live imaging of intra-lysosome pH in cell lines and primary neuronal culture using a novel genetically encoded biosensor.: 本研究提出了一种基因编码生物传感器,用于实时监测溶酶体 pH 值变化,可能通过 EGTA 等缓冲剂增强。这些发现可能就受钙螯合影响的细胞机制提供相关见解(Ponsford et al., 2021)。

  • Comparative Proteomic Analysis of Pleurotus ostreatus Reveals Great Metabolic Differences in the Cap and Stipe Development and the Potential Role of Ca(2+).: 本研究揭示了钙在真菌发育中的作用,而EGTA 可能通过钙螯合影响这些生物过程(Zhu et al., 2019)。


警告

毒性:标准处理(A)

重構

在复溶后存放于冰箱(4°C)。储备液可在4°C最长稳定1年。

其他說明

Lindenboim, L., et al. 1995.J. Neurochem.64, 1054.
Bers, D.M.1982.Am. J. Physiol.242, C404.

法律資訊

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 2


分析證明 (COA)

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    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
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      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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