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重要文件

219007

Sigma-Aldrich

半胱天冬酶抑制剂VI

Z-VAD-FMK, CAS 161401-82-7, is an irreversible pan caspase inhibitor. Does not require pretreatment with esterase for in vitro studies.

同義詞:

半胱天冬酶抑制剂VI, Z-VAD-FMK

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About This Item

經驗公式(希爾表示法):
C21H28FN3O7
CAS號碼:
分子量::
453.46
MDL號碼:
分類程式碼代碼:
12352200
NACRES:
NA.54
暫時無法取得訂價和供貨情況

品質等級

化驗

≥98% (HPLC)

形狀

solid

製造商/商標名

Calbiochem®

儲存條件

OK to freeze
desiccated

顏色

off-white

溶解度

DMSO: 9 mg/mL

運輸包裝

ambient

儲存溫度

−20°C

SMILES 字串

FCC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)OCc1ccccc1)C(C)C)C)CC(=O)O

InChI

1S/C21H28FN3O7/c1-12(2)18(25-21(31)32-11-14-7-5-4-6-8-14)20(30)23-13(3)19(29)24-15(9-17(27)28)16(26)10-22/h4-8,12-13,15,18H,9-11H2,1-3H3,(H,23,30)(H,24,29)(H,25,31)(H,27,28)/t13-,15-,18-/m0/s1

InChI 密鑰

SUUHZYLYARUNIA-YEWWUXTCSA-N

一般說明

不可逆的一般半胱天冬酶抑制剂。可用于涉及重组、分离和纯化的半胱天冬酶的研究。与半胱天冬酶抑制剂I(目录编号627610)不同,该抑制剂不需要用酯酶进行预处理即可进行体外研究。也可获得10 mM(1 mg/221 µl)半胱天冬酶抑制剂VI的DMSO溶液(目录号219011)。

生化/生理作用

产物不与ATP竞争。
可逆:否
细胞渗透性:否

警告

毒性:标准处理(A)

法律資訊

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析證明 (COA)

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