推薦產品
品質等級
化驗
≥70% (51V-NMR)
形狀
solid
效力
14 nM IC50
製造商／商標名
Calbiochem®
儲存條件
OK to freeze
protect from light
顏色
yellow
溶解度
water: 4 mg/mL
運輸包裝
ambient
儲存溫度
−20°C
一般說明
一种有效的磷酸酪氨酸磷酸酶抑制剂。激活肝癌细胞的胰岛素受体激酶（IRK）。还刺激分离的脂肪细胞中的脂肪生成。还报道了有效抑制PTEN（IC50=14 nM）。
生化／生理作用
主要靶标
PTEN
PTEN
产物不与ATP竞争。
可逆：否
细胞渗透性：否
包裝
用惰性气体包装
警告
毒性：标准处理（A）
重構
溶液中不稳定；仅在使用前进行复溶。
其他說明
Schmid, A.C., et al. 2004.FEBS Lett.566, 35.
Posner, B.I., et al. 1994.J. Biol. Chem. 269, 4596.
Posner, B.I., et al. 1994.J. Biol. Chem. 269, 4596.
法律資訊
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
分析證明 (COA)
輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號，寫有 ‘Lot’或‘Batch’.。
Zeinab Ghezelayagh et al.
Journal of assisted reproduction and genetics, 39(8), 1739-1747 (2022-07-13)
The effect of PTEN inhibitor (Bpv(HOpic); Bpv) and mTOR activators (phosphatidic acid (PA) and propranolol (PP)), were evaluated on the activation and subsequent development of human primordial follicles in ovarian tissue culture. Slow frozen-thawed human ovarian cortical strips were incubated
Amit Kumar et al.
Molecular and cellular biology, 44(7), 261-272 (2024-06-03)
The protein tyrosine phosphatase Src homology region 2 domain-containing phosphatase-1 (SHP-1) plays an important role in modulating glucose and lipid homeostasis. We previously suggested a potential role of SHP-1 in the regulation of peroxisome proliferator-activated receptor γ2 (PPARγ2) expression and
Cyrine Ben Dhaou et al.
Angiogenesis (2021-09-16)
Chemerin is a multifunctional protein initially characterized in our laboratory as a chemoattractant factor for leukocyte populations. Its main functional receptor is CMKLR1. We identified previously chemerin as an anti-tumoral factor inhibiting the vascularization of tumor grafts. We show here
我們的科學家團隊在所有研究領域都有豐富的經驗，包括生命科學、材料科學、化學合成、色譜、分析等.
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