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品質等級
製造商／商標名
Upstate®
技術
activity assay: suitable
affinity binding assay: suitable
NCBI登錄號
UniProt登錄號
運輸包裝
dry ice
基因資訊
human ... RAP1GDS1(5910)
包裝
Kit capacity: 20-30 assays
成分
100X GTPγS, 10mM (Cat.# 20-176)
100X GDP, 100mM (Cat.# 20-177)
Rap1 Activation Lysis Buffer, 2X
Anti-Rap1
Rap1 Assay Reagent (Ral GDS-RBD, agarose) (Cat.# 14-455)
100X GDP, 100mM (Cat.# 20-177)
Rap1 Activation Lysis Buffer, 2X
Anti-Rap1
Rap1 Assay Reagent (Ral GDS-RBD, agarose) (Cat.# 14-455)
品質
Routinely evaluated by affinity precipitation assay. Ral GDS RBD, agarose precipitated GTP-Rap1 from HEK293 lysates. The precipitated GTP-Rap1 was detected by immunoblot analysis using Anti-Rap1.
法律資訊
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
免責聲明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
訊號詞
Warning
危險聲明
危險分類
Eye Irrit. 2
儲存類別代碼
10 - Combustible liquids
分析證明 (COA)
輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號，寫有 ‘Lot’或‘Batch’.。
Uma Potla et al.
The Journal of clinical investigation, 124(4), 1757-1769 (2014-03-20)
Injury to the specialized epithelial cells of the glomerulus (podocytes) underlies the pathogenesis of all forms of proteinuric kidney disease; however, the specific genetic changes that mediate podocyte dysfunction after injury are not fully understood. Here, we performed a large-scale
Emilie Montenont et al.
Blood advances, 5(9), 2362-2374 (2021-05-05)
Human anucleate platelets cannot be directly modified using traditional genetic approaches. Instead, studies of platelet gene function depend on alternative models. Megakaryocytes (the nucleated precursor to platelets) are the nearest cell to platelets in origin, structure, and function. However, achieving
Xi Su et al.
Cell death & disease, 13(3), 218-218 (2022-03-11)
Thyroid cancer (TC) is one of the most common malignancies involving the head and neck, and its incidences are increasing every year. Small G protein signaling modulators 2 (SGSM2) belongs to a newly identified protein group that contributes to numerous
Differential interaction of the ras family GTP-binding proteins H-Ras, Rap1A, and R-Ras with the putative effector molecules Raf kinase and Ral-guanine nucleotide exchange factor
Herrmann, C, et al
The Journal of Biological Chemistry, 271, 6794-6800 (1996)
Rasmus Koefoed Petersen et al.
Molecular and cellular biology, 28(11), 3804-3816 (2008-04-09)
Cyclic AMP (cAMP)-dependent processes are pivotal during the early stages of adipocyte differentiation. We show that exchange protein directly activated by cAMP (Epac), which functions as a guanine nucleotide exchange factor for the Ras-like GTPases Rap1 and Rap2, was required
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