1.37156

吡哆醇 盐酸盐

EMPROVE^® EXPERT, Ph. Eur., BP, JP, USP, FCC

• 同義詞: PN HCl, 吡哆醇 盐酸盐, 抗皮炎素 盐酸盐, 维生素 B₆ 盐酸盐
• 經驗公式（希爾表示法）: C₈H₁₁NO₃ · HCl
• CAS號碼: 58-56-0
• 分子量：: 205.64
• Beilstein: 3632435
• MDL號碼: MFCD00012807
• 分類程式碼代碼: 41116107

屬性

• agency: BP; JP; Ph. Eur.; USP
• 品質等級: 500
• 法律遵循: FCC
• 產品線: EMPROVE^® EXPERT
• mp: 214-215 °C (lit.)
• 應用: clinical nutrition; liquid formulation; parenterals; pharmaceutical; vitamins, nutraceuticals, and natural products
• 儲存溫度: 15-25°C
• SMILES 字串: Cl[H].Cc1ncc(CO)c(CO)c1O
• InChI: 1S/C8H11NO3.ClH/c1-5-8(12)7(4-11)6(3-10)2-9-5;/h2,10-12H,3-4H2,1H3;1H
• InChI 密鑰: ZUFQODAHGAHPFQ-UHFFFAOYSA-N

描述

一般說明

For protein-based therapeutics, such as monoclonal antibodies (mAbs) or plasma derived proteins, often highly concentrated protein formulations are required to meet intended dosing regimens. However, this usually comes with elevated viscosities and presents a challenge in the manufacturing process and final formulation. Our Viscosity Reduction Excipient Platform reduces the viscosity and helps overcome challenges associated with highly concentrated protein solutions.
As part of our Emprove® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation.
Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

應用

The Viscosity Reduction Platform is based on the combination of two new excipients, one amino acid component with one anionic component, that together can better reduce protein viscosity beyond levels achieved with single excipients. Also, combining the two components enables a balance of viscosity reduction and protein stabilization. Pyridoxine hydrochloride Emprove® Expert is part of this new proprietary technology platform. Also, Pyridoxine hydrochloride (Vitamin B6) is used in clinical nutrition for treatment of vitamin B6 deficiency, anemia, mental retardation, Parkinson′s syndrome, gestational diabetes, tetanus and atherosclerosis.

包裝

1.37156.0100 / 100g / PE bottle
1.37156.1000 / 1kg / PE bottle
1.37156.9012 / 12kg / PE bucket

法律資訊

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

安全資訊

• 象形圖: GHS05
• 訊號詞: Danger
• 危險聲明: H318
• 防範說明: P280 - P305 + P351 + P338
• 危險分類: Eye Dam. 1
• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 1
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable