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Merck

1.06757

SAFC

4-羟基苯甲酸甲酯

EMPROVE® ESSENTIAL, Ph. Eur., BP, JP, NF

製藥生產

同義詞:

Methyl 4-hydroxybenzoate, Methylparaben, 4-Hydroxybenzoic acid methyl ester

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About This Item

線性公式:
4-(OH)C6H4(COOCH3)
CAS號碼:
分子量::
152.15
MDL號碼:
分類程式碼代碼:
12352108
酶委員會索引編號:
202-785-7

agency

BP
JP
NF
Ph. Eur.

品質等級

蒸汽壓力

0.000005 hPa ( 20 °C)

產品線

EMPROVE® ESSENTIAL

化驗

99.0-100.5% (HPLC)
99.0-102.0% (acidimetric)

形狀

solid

自燃溫度

>600 °C

技術

API processing | cocrystal formation: suitable

pH值

5.8 (20 °C in H2O, saturated solution)

mp

125 °C

溶解度

1.88 g/L

密度

1.38 g/cm3 at 20 °C

應用

liquid formulation
ophthalmics
pharmaceutical
semi-solid formulation
solid formulation

儲存溫度

15-25°C

InChI

1S/C8H8O3/c1-11-8(10)6-2-4-7(9)5-3-6/h2-5,9H,1H3

InChI 密鑰

LXCFILQKKLGQFO-UHFFFAOYSA-N

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一般說明

Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge in formulation. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our Emprove® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

應用

Methyl 4-hydroxybenzoate has antimicrobial characteristics and is used as preservative in pharmaceutical formulations and cosmetics. It can be combined with other parabens like propyl 4-hydroxybenzoate or ethyl 4-hydroxybenzoate.

法律資訊

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

免責聲明

The product is not intended for use as a biocide under global biocide regulations, including but not limited to US EPA′s Federal Insecticide Fungicide and Rodenticide Act, European Biocidal Products Regulation, Canada’s Pest Management Regulatory Agency, Turkey’s Biocidal Products Regulation, Korea’s Consumer Chemical Products and Biocide Safety Management Act (K-BPR) and others.

象形圖

Environment

危險聲明

防範說明

危險分類

Aquatic Chronic 2

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 1

閃點(°F)

334.4 °F

閃點(°C)

168 °C


分析證明 (COA)

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