1.06187

葡甲胺

EMPROVE^® EXPERT, Ph. Eur., ChP, JP, USP

• 同義詞: N -甲基- D -葡胺, 1-去氧-1-(甲胺)-D-山梨醇, 葡甲胺
• 經驗公式（希爾表示法）: C₇H₁₇NO₅
• CAS號碼: 6284-40-8
• 分子量：: 195.21
• Beilstein: 385906
• MDL號碼: MFCD00004707
• 分類程式碼代碼: 12352104
• 酶委員會索引編號: 228-506-9

屬性

• agency: ChP; JP; Ph. Eur.; USP
• 品質等級: 500
• 產品線: EMPROVE^® EXPERT
• 形狀: solid
• 自燃溫度: ~662 °F
• pH值: 11 (20 °C, 10 g/L in H₂O)
• bp: 210 °C/1013 hPa
• mp: 129-131.5 °C (lit.)
• 應用: liquid formulation; pharmaceutical; solid formulation; solubility enhancement
• 儲存溫度: no temp limit
• SMILES 字串: CNC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO
• InChI: 1S/C7H17NO5/c1-8-2-4(10)6(12)7(13)5(11)3-9/h4-13H,2-3H2,1H3/t4-,5+,6+,7+/m0/s1
• InChI 密鑰: MBBZMMPHUWSWHV-BDVNFPICSA-N

描述

一般說明

When working on a pharmaceutical formulation, there are specific considerations to make and challenging hurdles to take before you can successfully launch your final drug product - formulation stability, release kinetics and bioavailability limitations just to name a few. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our Emprove^® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC^® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

應用

Meglumine Emprove^® Essential is a robust pharmaceutical excipient that can provide stability, solubility enhancement and pH modification in solid and liquid formulations.

特點和優勢

• Solubility and bioavailability enhancement of APIs
• Excellent counterion performance, a viable alternative to sodium
• API grade: manufactured under the cGMP ICH Q7 guideline for APIs
• Sole manufacturing location for API-grade meglumine in Europe
• Multi-compendial product, complying with all major pharmacopeias, including ChP
• Meglumine Emprove^® API has also been successfully co-reviewed in China

法律資訊

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

安全資訊

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 1
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable