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Merck
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文件

07-877

Sigma-Aldrich

Anti-phospho-PKCη (Thr655) Antibody

Upstate®, from rabbit

同義詞:

PRKCH, PKCeta, PKCh, protein kinase C, eta, KPCL

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About This Item

分類程式碼代碼:
12352203
eCl@ss:
32160702
NACRES:
NA.41

生物源

rabbit

品質等級

100

抗體表格

affinity isolated antibody

抗體產品種類

primary antibodies

無性繁殖

polyclonal

純化經由

affinity chromatography

物種活性

human

製造商／商標名

Upstate®

技術

western blot: suitable

同型

IgG

NCBI登錄號

NM_006255.3

UniProt登錄號

P24723

運輸包裝

dry ice

目標翻譯後修改

phosphorylation (pThr655)

基因資訊

human ... PRKCH(5583)

特異性

Predicted to cross-react with Mouse and Rat (100% homologous) based on sequence homology.
Recognizes phosphorylated PKCη (Thr655). Not expected to cross-react with other PKC isoforms

免疫原

Peptide corresponding to amino acid region encompassing the human, mouse, and rat phospho-PKCη (Thr655).

應用

Immunoblot Analysis: A 0.50 μg/mL dilution of this lot detected phospho-PKCη (Thr655) in RIPA lysate of PMA treated Jurkat cells.
Research Category
Signaling
Research Sub Category
Cytoskeletal Signaling
This Anti-phospho-PKCη (Thr655) Antibody is validated for use in WB for the detection of phospho-PKCη (Thr655).

品質

Routinely evaluated by immunoblot.

標靶描述

~80 kDa

外觀

Affinity purified
100 μL of affinity purified rabbit polyclonal IgG in 50% storage buffer (PBS (without Mg2+ and Ca2+), pH 7.3 containing 1.0 mg/mL BSA (IgG, protease free) and 0.05% sodium azide).

儲存和穩定性

Stable for 2 years at -80°C from date of shipment. Upon first thaw, and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -80°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.

法律資訊

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

12 - Non Combustible Liquids

水污染物質分類（WGK）

WGK 1

閃點（°F）

Not applicable

閃點（°C）

Not applicable

分析證明 (COA)

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Keisuke Taniuchi et al.
PloS one, 7(4), e35674-e35674 (2012-04-26)
A novel function for the binder of Arl two (BART) molecule in pancreatic cancer cells is reported. BART inhibits invasiveness of pancreatic cancer cells through binding to a Ca(2+)-dependent, phosphorylated, guanosine triphosphatase (GTPase) membrane fusion protein, annexin7 (ANX7). A tumor
Peter Gruber et al.
Journal of biochemistry, 149(3), 331-336 (2010-12-28)
Protein kinase C (PKC) is a family of at least 10 isozymes involved in the activation of different signal transduction pathways. The exact function of these isozymes is not known at present. Isozyme-selective inhibitors would be important to explain the

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