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Merck
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07-678

Sigma-Aldrich

Anti-LINGO-1 Antibody

Upstate®, from rabbit

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About This Item

分類程式碼代碼:
12352203
eCl@ss:
32160702
NACRES:
NA.41

生物源

rabbit

品質等級

抗體表格

purified antibody

抗體產品種類

primary antibodies

無性繁殖

polyclonal

物種活性

mouse, human, rat

製造商/商標名

Upstate®

技術

western blot: suitable

同型

IgG

NCBI登錄號

UniProt登錄號

運輸包裝

dry ice

目標翻譯後修改

unmodified

基因資訊

mouse ... Lingo1(235402)

特異性

LINGO-1

免疫原

KLH-conjugated, synthetic peptide corresponding to amino acid residues 611-620 of human LINGO-1 (APRKFNMKMI)

應用

Detect LINGO-1 using this Anti-LINGO-1 Antibody validated for use in WB.
Research Category
Neuroscience
Research Sub Category
Neurodegenerative Diseases

品質

routinely evaluated by immunoblot on mouse brain membrane samples.

標靶描述

Mr ~83kDa

外觀

Protein A purified
Format: Purified

儲存和穩定性

stable for 2 years at -20°C from date of shipment

法律資訊

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 2


分析證明 (COA)

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Lingo-1 expression is increased in essential tremor cerebellum and is present in the basket cell pinceau.
Kuo, SH; Tang, G; Louis, ED; Ma, K; Babji, R; Balatbat, M; Cortes, E; Vonsattel et al.
Acta neuropathologica null
Sha Mi et al.
Nature neuroscience, 7(3), 221-228 (2004-02-18)
Axon regeneration in the adult CNS is prevented by inhibitors in myelin. These inhibitors seem to modulate RhoA activity by binding to a receptor complex comprising a ligand-binding subunit (the Nogo-66 receptor NgR1) and a signal transducing subunit (the neurotrophin
Alexandra Trifunovski et al.
Neuroreport, 15(15), 2397-2400 (2005-01-11)
Axonal regeneration after injury can be limited in the adult CNS by the presence of inhibitory proteins such as Nogo. Nogo binds to a receptor complex that consists of Nogo receptor (NgR), p75NTR, and Lingo-1. Nogo binding activates RhoA, which
From cell death to neuronal regeneration, effects of the p75 neurotrophin receptor depend on interactions with partner subunits.
Bandtlow, Christine and Dechant, Georg
Science's STKE : Signal Transduction Knowledge Environment, 2004, pe24-pe24 (2004)
Multi-tasking by the p75 neurotrophin receptor: sortilin things out?
Bronfman, Francisca C and Fainzilber, Mike
EMBO Reports, 5, 867-871 (2004)

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