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Merck
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05-561

Sigma-Aldrich

Anti-LAT Antibody, clone 2E9

clone 2E9, Upstate®, from mouse

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About This Item

分類程式碼代碼:
12352203
eCl@ss:
32160702
NACRES:
NA.41

生物源

mouse

品質等級

抗體表格

purified immunoglobulin

抗體產品種類

primary antibodies

無性繁殖

2E9, monoclonal

物種活性

human

製造商/商標名

Upstate®

技術

immunoprecipitation (IP): suitable
western blot: suitable

同型

IgG

NCBI登錄號

UniProt登錄號

運輸包裝

wet ice

目標翻譯後修改

unmodified

基因資訊

human ... LAT(27040)

特異性

Recognizes both forms of LAT.

免疫原

GST fusion protein corresponding to residues 31-233 of human LAT

應用

Detect LAT using this Anti-LAT Antibody, clone 2E9 validated for use in IP & WB.
Research Category
Inflammation & Immunology
Research Sub Category
Immunoglobulins & Immunology

品質

routinely evaluated by immunoblot on RIPA lysates from Jurkat cells

標靶描述

36/38 kDa

外觀

Protein G Purified
Format: Purified
Protein A Purified immunoglobulin in Protein A Purified immunoglobulin in 0.1M Tris-Glycine, 0.15M NaCl and 0.05% Sodium Azide.

儲存和穩定性

Stable for 1 year at 2-8°C from date of receipt.

分析報告

Control
Positive Antigen Control: Catalog #12-303, Jurkat cell lysate.

法律資訊

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 1


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Derek D Sloan et al.
Journal of virology, 81(22), 12504-12514 (2007-09-07)
Herpes simplex virus (HSV)-specific T cells are essential for viral clearance. However, T cells do not prevent HSV latent infection or reactivation, suggesting that HSV has the potential to modulate T-cell function. T-cell receptor (TCR) stimulation is a potent and
Fatoumata Samassa et al.
Cellular microbiology, 22(5), e13166-e13166 (2020-01-21)
Strategies employed by pathogenic enteric bacteria, such as Shigella, to subvert the host adaptive immunity are not well defined. Impairment of T lymphocyte chemotaxis by blockage of polarised edge formation has been reported upon Shigella infection. However, the functional impact
Ruth Seggewiss et al.
Blood, 105(6), 2473-2479 (2004-12-02)
The tyrosine kinase inhibitor imatinib (imatinib, STI571, Glivec, and Gleevec) is increasingly used in patients undergoing allogeneic transplantation for leukemia. However, little is known regarding its potential immunoregulatory effects. Here, we investigate the effect of imatinib on T-cell receptor (TCR)-mediated
Nupura Hirve et al.
PloS one, 7(9), e45158-e45158 (2012-10-03)
Binding of the membrane phospholipid phosphatidylinositol 3,4,5-trisphosphate (PIP(3)) to the Pleckstrin Homology (PH) domain of the Tec family protein tyrosine kinase, Inducible T cell Kinase (ITK), is critical for the recruitment of the kinase to the plasma membrane and its
W Zhang et al.
Cell, 92(1), 83-92 (1998-03-07)
Despite extensive study, several of the major components involved in T cell receptor-mediated signaling remain unidentified. Here we report the cloning of the cDNA for a highly tyrosine-phosphorylated 36-38 kDa protein, previously characterized by its association with Grb2, phospholipase C-gamma1

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