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重要文件

E-075

Supelco

雌酚酮 溶液

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

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About This Item

經驗公式(希爾表示法):
C18H22O2
CAS號碼:
分子量::
270.37
MDL號碼:
分類程式碼代碼:
41116107
PubChem物質ID:
NACRES:
NA.24
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等級

certified reference material

品質等級

形狀

liquid

特點

Snap-N-Spike®/Snap-N-Shoot®

包裝

ampule of 1 mL

製造商/商標名

Cerilliant®

濃度

1.0 mg/mL in methanol

技術

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

應用

clinical testing
clinical testing

形式

single component solution

儲存溫度

−20°C

SMILES 字串

CC12CCC3C(CCc4cc(O)ccc34)C1CCC2=O

InChI

1S/C18H22O2/c1-18-9-8-14-13-5-3-12(19)10-11(13)2-4-15(14)16(18)6-7-17(18)20/h3,5,10,14-16,19H,2,4,6-9H2,1H3/t14-,15-,16+,18+/m1/s1

InChI 密鑰

DNXHEGUUPJUMQT-CBZIJGRNSA-N

基因資訊

human ... ESR1(2099)

一般說明

通过LC-MS/MS或GC/MS监测血清或血浆中雌二醇,雌酮的前体,以评估和诊断女性的发育异常,酶失活或缺乏,多囊卵巢综合征(PCOS)或激素替代疗法。

應用


  • 用于治疗酵母菌感染的氟康唑溶液:由于其对酵母菌感染的疗效,特别是对外阴阴道念珠菌病的疗效,氟康唑得到了广泛使用。它抑制麦角固醇的合成,而麦角固醇的合成对真菌细胞膜的完整性至关重要,因此氟康唑具有抗真菌作用(Picheta et al., 2024)。

  • 全身性念珠菌病的抗真菌药物:氟康唑溶液对于全身性念珠菌病的治疗至关重要,它提供了一种强效抗真菌机制,可以降低真菌细胞膜的麦角固醇含量,而麦角固醇含量对于真菌细胞活力的维持至关重要(Dettlaff et al., 2024)。

  • 氟康唑体外抗真菌活性检测法的开发:氟康唑用于体外抗真菌活性检测法的开发,这些检测对于潜在抗真菌药物的筛选及其对各种真菌病原体疗效的评估至关重要(Teba et al., 2024)。


法律資訊

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

訊號詞

Danger

危險分類

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

標靶器官

Eyes,Central nervous system

儲存類別代碼

3 - Flammable liquids

水污染物質分類(WGK)

WGK 2

閃點(°F)

49.5 °F - closed cup

閃點(°C)

9.7 °C - closed cup


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