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C-045

Supelco

大麻二酚标准液 溶液

Cannabidiol solution

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

同義詞:

CBD

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About This Item

經驗公式（希爾表示法）:
C21H30O2
CAS號碼:
13956-29-1
分子量：:
314.46
EC號碼:
200-659-6
MDL號碼:
MFCD00869597
分類程式碼代碼:
41116107
PubChem物質ID:
329774791
NACRES:
NA.24
暫時無法取得訂價和供貨情況

等級

certified reference material

品質等級

300

形狀

liquid

特點

SNAP-N-SPIKE®, SNAP-N-SHOOT®

包裝

ampule of 1 mL

製造商／商標名

Cerilliant®

濃度

1.0 mg/mL in methanol

技術

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

應用

cannabis testing
cannabis testing

形式

single component solution

儲存溫度

−20°C

SMILES 字串

CCCCCc1cc(O)c([C@@H]2C=C(C)CC[C@H]2C(C)=C)c(O)c1

InChI

1S/C21H30O2/c1-5-6-7-8-16-12-19(22)21(20(23)13-16)18-11-15(4)9-10-17(18)14(2)3/h11-13,17-18,22-23H,2,5-10H2,1,3-4H3/t17-,18+/m0/s1

InChI 密鑰

QHMBSVQNZZTUGM-ZWKOTPCHSA-N

基因資訊

human ... CNR1(1268)

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相關類別

一般說明

该认证加标溶液® 适用于通过 HPLC、GC/MS 或 LC-MS/MS 法进行大麻二酚测定，从而用于法医分析、临床毒理学、尿液药物测试和大麻效力或杂质分析测试等应用。

大麻二酚（CBD）是大麻科植物中发现的重要大麻素之一，以其非精神活性特性而闻名。它在光或热的作用下由前体大麻二酚酸脱羧形成。它具有多种治疗特性，如抗氧化、抗炎、抗菌、神经保护、抗焦虑和抗惊厥作用。

應用

该认证标准物质（CRM）还可作如下用途：
  • 使用反相高效液相色谱（RP-HPLC）结合二极管阵列检测器（DAD）测定油基质中放入 4 种大麻素
  • 开发和验证基于液相色谱-串联质谱（LC-MS/MS）的技术，用于测量大鼠高剂量大麻二酚全血样品中的大麻二酚、∆9-四氢大麻酚及其代谢物
  • 使用等密度 RP-HPLC 结合 UV 检测法同时测定不同大麻油产品中的大麻二酚和四氢大麻酚
  • 通过液-液萃取（LLE）后跟气相色谱-质谱法对头发样品中的 Δ9-四氢大麻酚、大麻酚和大麻二酚进行多重分析
  • 超声辅助提取三种不同商业外用产品中的大麻二酚，并以 GC-MS 法测定

特點和優勢

  • 完全符合 ISO/IEC 17025 和 ISO 17034 认证
  • 附综合分析证书（CoA），包括稳定性、均匀性、浓度准确性、不确定性和可追溯性数据
  • 通过实时稳定性研究严格测试，以确保准确性和保质期
  • 使用合格的精密天平进行重量准备，以确保最小不确定性
  • 氩气环境下火焰密封，装入安瓿以便长期保存
  • 提供方便的 DEA 豁免格式，以提高实验室效率

法律資訊

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
CERTIFIED SPIKING SOLUTION is a registered trademark of Cerilliant Corporation
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

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訊號詞

Danger

危險分類

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

標靶器官

Eyes,Central nervous system

儲存類別代碼

3 - Flammable liquids

水污染物質分類（WGK）

WGK 2

閃點（°F）

49.5 °F - closed cup

閃點（°C）

9.7 °C - closed cup

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分析證明 (COA)

Lot/Batch Number

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R B Laprairie et al.
British journal of pharmacology, 172(20), 4790-4805 (2015-07-29)
Cannabidiol has been reported to act as an antagonist at cannabinoid CB1 receptors. We hypothesized that cannabidiol would inhibit cannabinoid agonist activity through negative allosteric modulation of CB1 receptors. Internalization of CB1 receptors, arrestin2 recruitment, and PLCβ3 and ERK1/2 phosphorylation
Raymond J M Niesink et al.
Addiction (Abingdon, England), 110(12), 1941-1950 (2015-08-04)
Between 2000 and 2005 the average percentage of Δ(9) -tetrahydrocannabinol (THC) in marijuana as sold in Dutch coffeeshops has increased substantially; the potency of domestic products (Nederwiet and Nederhasj) has particularly increased. In contrast with imported marijuana, Nederwiet hardly contained
Marcos Hortes N Chagas et al.
Journal of psychopharmacology (Oxford, England), 27(3), 312-316 (2013-01-25)
Cannabidiol (CBD) is one of the main components of Cannabis sativa and has a wide spectrum of action, including effects in the sleep-wake cycle. The objective of this paper is to assess the effects on sleep of acute systemic administration
Liliana Soroceanu et al.
Cancer research, 73(5), 1559-1569 (2012-12-18)
Glioblastoma is the most common form of primary adult brain tumors. A majority of glioblastomas grow invasively into distant brain tissue, leading to tumor recurrence, which is ultimately incurable. It is, therefore, essential to discover master regulators that control glioblastoma
Alline Cristina Campos et al.
Psychopharmacology, 226(1), 13-24 (2012-09-26)
Cannabidiol (CBD) is a non-psychotomimetic constituent of Cannabis sativa plant that promotes antianxiety and anti-panic effects in animal models after acute systemic or intra-dorsal periaqueductal gray (DPAG) administration. However, the effects of CBD repeated administration, and the possible mechanisms involved
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