跳轉至內容
Merck
全部照片(1)

重要文件

檢視所有文件

LM1900

Avanti

17:0-20:4pi (3) P

Avanti Research™ - A Croda Brand

同義詞:

1-heptadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-(1′-myo-inositol-3′-phosphate) (ammonium salt)

登入查看組織和合約定價
全部照片(1)

About This Item

經驗公式（希爾表示法）:
C46H88N2O16P2
CAS號碼:
1246304-67-5
分子量：:
987.14
分類程式碼代碼:
12352211
NACRES:
NA.25
暫時無法取得訂價和供貨情況

形狀

powder

製造商／商標名

Avanti Research™ - A Croda Brand

包裝

1 ea of 1 × (with stopper and crimp cap (LM1900-1EA))

應用

lipidomics
metabolomics

運輸包裝

dry ice

儲存溫度

−20°C

SMILES 字串

[H][C@@](COP([O-])(O[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](OP([O-])(O)=O)[C@H]1O)=O)(OC(CCC/C=C\C/C=C\C/C=C\C/C=C\CCCCC)=O)COC(CCCCCCCCCCCCCCCC)=O.[NH4+].[NH4+]

InChI 密鑰

IOJKXWHTFCVKEI-DOKNWMIYSA-N

一般說明

17:0-20:4 PI(3)P, phosphatidylinositol 3?phosphate, is the predominant phosphoinositide localized in endosomes and yeast vacuoles.[1] It is synthesized by phosphatidylinositol 3?kinase (PI3K) from phosphatidylinositol.[1][2]

應用

17:0-20:4 PI(3)P has been used as an internal standard for targeted lipidomic analysis.[3]

生化／生理作用

17:0-20:4 PI(3)P plays a vital role in intracellular membrane trafficking and recruitment of effector proteins, which possess PI(3)P-binding motifs to membranes.[1][2] It also regulates the formation of autophagosomes.[4]

包裝

2 mL Amber Serum Vial with Stopper and Crimp Cap (LM1900-1EA)

法律資訊

Avanti Research is a trademark of Avanti Polar Lipids, LLC

儲存類別代碼

11 - Combustible Solids

從最近期的版本中選擇一個：

分析證明 (COA)

Lot/Batch Number

It looks like we've run into a problem, but you can still download Certificates of Analysis from our 文件 section.

如果您需要協助，請聯絡 客戶支援

已經擁有該產品？

您可以在文件庫中找到最近購買的產品相關文件。

存取文件庫

The Role of PI3P Phosphatases in the Regulation of Autophagy
Pruett ST, et al.
Febs Letters, 584(7), 1313-1318 (2010)
The spastic paraplegia-associated phospholipase DDHD1 is a primary brain phosphatidylinositol lipase
Inloes JM, et al.
Molecules (Basel), 57(39), 5759-5767 (2018)
The phosphatidylinositol 3?phosphate?binding FYVE finger
Stenmark H, et al.
Febs Letters, 513(1), 77-84 (2002)
G S Taylor et al.
Proceedings of the National Academy of Sciences of the United States of America, 97(16), 8910-8915 (2000-07-20)
The lipid second messenger phosphatidylinositol 3-phosphate [PI(3)P] plays a crucial role in intracellular membrane trafficking. We report here that myotubularin, a protein tyrosine phosphatase required for muscle cell differentiation, is a potent PI(3)P phosphatase. Recombinant human myotubularin specifically dephosphorylates PI(3)P
Jordon M Inloes et al.
Biochemistry, 57(39), 5759-5767 (2018-09-18)
Deleterious mutations in the serine hydrolase DDHD domain containing 1 (DDHD1) cause the SPG28 subtype of the neurological disease hereditary spastic paraplegia (HSP), which is characterized by axonal neuropathy and gait impairments. DDHD1 has been shown to display PLA1-type phospholipase

我們的科學家團隊在所有研究領域都有豐富的經驗，包括生命科學、材料科學、化學合成、色譜、分析等.

聯絡技術服務