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重要文件

LM1102

Avanti

17:0-20:4 PE

Avanti Research - A Croda Brand LM1102, methanol solution

同義詞:

1-heptadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphoethanolamine

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About This Item

經驗公式(希爾表示法):
C42H76NO8P
CAS號碼:
分子量::
754.03
分類程式碼代碼:
12352211
NACRES:
NA.25
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形狀

methanol solution

包裝

pkg of 1 × 1 mL (LM1102-1EA)

製造商/商標名

Avanti Research - A Croda Brand LM1102

濃度

~10 μg/mL (Refer to C of A for lot specific concentration.)

運輸包裝

dry ice

儲存溫度

−20°C

SMILES 字串

[H][C@@](COP([O-])(OCC[NH3+])=O)(OC(CCC/C=C\C/C=C\C/C=C\C/C=C\CCCCC)=O)COC(CCCCCCCCCCCCCCCC)=O

InChI

1S/C42H76NO8P/c1-3-5-7-9-11-13-15-17-19-20-21-23-25-27-29-31-33-35-42(45)51-40(39-50-52(46,47)49-37-36-43)38-48-41(44)34-32-30-28-26-24-22-18-16-14-12-10-8-6-4-2/h11,13,17,19,21,23,27,29,40H,3-10,12,14-16,18,20,22,24-26,28,30-39,43H2,1-2H3,(H,46,47)/b13-1

應用

17:0-20:4 PE or 1-heptadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphoethanolamine has been used as an internal standard:
  • for phospholipid extraction from mitochondria for quantitative mass spectrometry (MS) analysis[1]
  • for lipid analysis of murine brain lipid extract using Fourier transform-ion cyclotron resonance-mass spectrometry (FT-ICR-MS)[2]
  • for lipid quantification using liquid chromatography- mass spectrometry (LC-MS)[3][4]
  • in the preparation of total lipid extracts by LC-MS[5]
  • for ratiometric quantification of phosphoethanolamine (PE) using LC-MS[6]

生化/生理作用

Phosphoethanolamine (PE) acts as a substrate for several phospholipids of the cell membrane. It is associated with the phospholipid turnover. PE is also found to prevent tumor progression.[7]

包裝

2 mL Amber Glass Sealed Ampule (LM1102-1EA)

法律資訊

Avanti Research is a trademark of Avanti Polar Lipids, LLC

訊號詞

Danger

危險分類

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

標靶器官

Eyes

儲存類別代碼

3 - Flammable liquids

水污染物質分類(WGK)

WGK 2

閃點(°F)

49.5 °F - closed cup

閃點(°C)

9.7 °C - closed cup


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Andreas Ullen et al.
Free radical biology & medicine, 49(11), 1655-1665 (2010-09-03)
Plasmalogens, 1-O-alk-1'-enyl-2-acyl-sn-glycerophospholipids, are significant constituents of cellular membranes and are essential for normal brain development. Plasmalogens, which contain a vinyl ether bond at the sn-1 position, are preferential targets for hypochlorous acid (HOCl), generated by myeloperoxidase (MPO) from H(2)O(2) and
Kallol Gupta et al.
Nature protocols, 13(5), 1106-1120 (2018-04-28)
With the recent success in determining membrane protein structures, further detailed understanding of the identity and function of the bound lipidome is essential. Using an approach that combines high-energy native mass spectrometry (HE-nMS) and solution-phase lipid profiling, this protocol can
Di Ding et al.
Molecular neurobiology, 56(4), 2618-2639 (2018-07-28)
Neurons from the adult central nervous system (CNS) demonstrate limited mRNA transport and localized protein synthesis versus developing neurons, correlating with lower regenerative capacity. We found that deimination (posttranslational conversion of protein-bound arginine into citrulline) undergoes upregulation during early neuronal
Laura Montani et al.
The Journal of cell biology, 217(4), 1353-1368 (2018-02-13)
Myelination calls for a remarkable surge in cell metabolism to facilitate lipid and membrane production. Endogenous fatty acid (FA) synthesis represents a potentially critical process in myelinating glia. Using genetically modified mice, we show that Schwann cell (SC) intrinsic activity
Adilson Kleber Ferreira et al.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 67(6), 481-487 (2013-06-19)
Phosphoethanolamine (Pho-s) is a compound involved in phospholipid turnover, acting as a substrate for many phospholipids of the cell membranes. In a recent study, we showed that Pho-s has antitumor effect in the several tumor cells. In this study we

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