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999974P

Avanti

16:0-18:1 Diether PE

Avanti Research - A Croda Brand 999974P, powder

同義詞:

1-O-hexadecanyl-2-O-(9Z-octadecenyl)-sn-glycero-3-phosphoethanolamine

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About This Item

經驗公式(希爾表示法):
C39H80 NO6 P
CAS號碼:
分子量::
690.03
分類程式碼代碼:
51191904
NACRES:
NA.25

形狀

powder

包裝

pkg of 1 × 10 mg (999974P-10mg)

製造商/商標名

Avanti Research - A Croda Brand 999974P

脂質類型

cardiolipins
phospholipids

運輸包裝

dry ice

儲存溫度

−20°C

SMILES 字串

[O-]P(OCC[NH3+])(OC[C@]([H])(OCCCCCCCC/C=C\CCCCCCCC)COCCCCCCCCCCCCCCCC)=O

InChI

1S/C39H80NO6P/c1-3-5-7-9-11-13-15-17-19-20-22-24-26-28-30-32-35-44-39(38-46-47(41,42)45-36-33-40)37-43-34-31-29-27-25-23-21-18-16-14-12-10-8-6-4-2/h17,19,39H,3-16,18,20-38,40H2,1-2H3,(H,41,42)/b19-17-/t39-/m1/s1

InChI 密鑰

QMGSXZBWJYQMDL-VEAYGOGPSA-N

一般說明

16:0-18:1 Diether PE or 1-O-hexadecanyl-2-O-(9Z-octadecenyl)-sn-glycero-3-phosphoethanolamine is a class of glycerophospholipids that have hexadecane and octadecene chains attached to the sn-1 and sn-2 positions of the glycerol backbone respectively by ether bonds. It has ethanolamine as the alcohol moiety, attached to the phosphate group.

生化/生理作用

Certain important signaling molecules are derived from ether linked phospholipids, which act as precursors. 20 percent of the total phospholipids in human are ether linked phospholipids. Inborn errors hindering the synthesis of ether phospholipids might lead to pathological conditions. Phosphoethanolamines (PEs) serve as a substrate for several phospholipids of the cell membrane. They are associated with the phospholipid turnover. PEs are also found to prevent tumor progression.

包裝

5 mL Clear Glass Sealed Ampule (999974P-10mg)

法律資訊

Avanti Research is a trademark of Avanti Polar Lipids, LLC

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

No data available

閃點(°C)

No data available


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Ether-linked lipids and their bioactive species
Biochemistry of Lipids, Lipoproteins and Membranes, 245-276 (2008)
John M Dean et al.
Protein & cell, 9(2), 196-206 (2017-05-20)
Ether lipids, such as plasmalogens, are peroxisome-derived glycerophospholipids in which the hydrocarbon chain at the sn-1 position of the glycerol backbone is attached by an ether bond, as opposed to an ester bond in the more common diacyl phospholipids. This
Adilson Kleber Ferreira et al.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 67(6), 481-487 (2013-06-19)
Phosphoethanolamine (Pho-s) is a compound involved in phospholipid turnover, acting as a substrate for many phospholipids of the cell membranes. In a recent study, we showed that Pho-s has antitumor effect in the several tumor cells. In this study we

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