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重要文件

880620P

Avanti

18:0 PEG750 PE

Avanti Research - A Croda Brand 880620P, powder

同義詞:

1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-750] (ammonium salt)

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About This Item

CAS號碼:
分類程式碼代碼:
12352211
NACRES:
NA.25
暫時無法取得訂價和供貨情況

形狀

powder

包裝

pkg of 1 × 200 mg (880620P-200mg)
pkg of 1 × 25 mg (880620P-25mg)

製造商/商標名

Avanti Research - A Croda Brand 880620P

運輸包裝

dry ice

儲存溫度

−20°C

SMILES 字串

[H][C@@](COP([O-])(OCCNC(OCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOC)=O)=O)(OC(CCCCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCCCC)=O.[NH4+]

InChI 密鑰

QAVSYMFTABOITA-CQZUBJGASA-N

一般說明

18:0 PEG750 PE is a polyethylene glycol (PEG) conjugated phospholipid. The molecular weight and exact mass are averages based on the polydispersity of PEG.

應用

18:0 PEG750 PE might be used to PEGylate lipoplexes and to study the feasibility of its entrapment into a solid matrix system for prolonged delivery of siRNA in vaginal mucus.[1]

生化/生理作用

18:0 PEG750 PE is useful as a micelle-forming component.[2]

包裝

20 mL Clear Glass Screw Cap Vial (880620P-200mg)
5 mL Clear Glass Sealed Ampule (880620P-25mg)

法律資訊

Avanti Research is a trademark of Avanti Polar Lipids, LLC

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3


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Tania Furst et al.
Journal of controlled release : official journal of the Controlled Release Society, 236, 68-78 (2016-06-23)
Topical vaginal sustained delivery of siRNA presents a significant challenge due to the short residence time of formulations. Therefore, a drug delivery system capable to adhere to the vaginal mucosa is desirable, as it could allow a prolonged delivery and
Rupa R Sawant et al.
International journal of pharmaceutics, 374(1-2), 114-118 (2009-05-19)
Cell-penetrating peptide (TATp) was attached to the distal tips of polyethyleneglycol (PEG) moieties of polyethyleneglycol-phosphatidylethanolamine (PEG-PE) micelles loaded with paclitaxel (PCT). The TATp-modified micelles demonstrated an increased interaction with cancer cells compared to non-modified micelles resulting in a significant increase

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