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860575P

Avanti

C8 L-threo-Lactosyl(β) Ceramide (d18:1/8:0)

Avanti Research - A Croda Brand 860575P, powder

同義詞:

D-lactosyl-β1-1′-N-octanoyl-L-threo-sphingosine

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About This Item

經驗公式(希爾表示法):
C38H71NO13
CAS號碼:
分子量::
749.97
MDL號碼:
分類程式碼代碼:
12352211
NACRES:
NA.25
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形狀

powder

包裝

pkg of 1 × 1 mg (860575P-1mg)

製造商/商標名

Avanti Research - A Croda Brand 860575P

脂質類型

sphingolipids

運輸包裝

dry ice

儲存溫度

−20°C

SMILES 字串

CCCCCCCCCCCCC/C=C/[C@@](O)([H])[C@@]([H])(NC(CCCCCCC)=O)CO[C@H](O1)[C@H](O)[C@@H](O)[C@@H]([C@H]1CO)O[C@H](O2)[C@H](O)[C@@H](O)[C@H]([C@H]2CO)O

InChI 密鑰

JUCWRRXMPGRQOG-CKTHHAJGSA-N

一般說明

C8 L-threo-Lactosyl(β) Ceramide (d18:1/8:0) is a synthetic glycosphingolipid (GSL) with nonnatural stereochemistry.

應用

C8 L-threo-Lactosyl(β) Ceramide (d18:1/8:0) may be used to disrupt brain-derived neurotropic factor (BDNF)-induced integrin clustering.[1]

生化/生理作用

C8 L-threo-Lactosyl(β) Ceramide (d18:1/8:0) is a caveolar uptake inhibitor, which blocks SV40 virus infection. It also prevents E1-integrin activation and downstream signaling.[1] C8 L-threo-Lactosyl(β) Ceramide (d18:1/8:0) can deter the aggregation of lipids and proteins into glycosphingolipids (GSLs) and cholesterol-enriched microdomains (rafts) at the plasma membrane (PM).

包裝

5 mL Amber Glass Screw Cap Vial (860575P-1mg)

法律資訊

Avanti Research is a trademark of Avanti Polar Lipids, LLC

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3


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Bidirectional remodeling of beta1-integrin adhesions during chemotropic regulation of nerve growth
Carlstrom LP, et al.
BMC biology, 9(1), 82-82 (2011)

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