推薦產品
形狀
powder
包裝
pkg of 1 × 1 mg (860575P-1mg)
製造商/商標名
Avanti Research™ - A Croda Brand 860575P
脂質類型
sphingolipids
運輸包裝
dry ice
儲存溫度
−20°C
SMILES 字串
CCCCCCCCCCCCC/C=C/[C@@](O)([H])[C@@]([H])(NC(CCCCCCC)=O)CO[C@H](O1)[C@H](O)[C@@H](O)[C@@H]([C@H]1CO)O[C@H](O2)[C@H](O)[C@@H](O)[C@H]([C@H]2CO)O
InChI 密鑰
JUCWRRXMPGRQOG-CKTHHAJGSA-N
一般說明
C8 L-threo-Lactosyl(β) Ceramide (d18:1/8:0) is a synthetic glycosphingolipid (GSL) with nonnatural stereochemistry.
應用
C8 L-threo-Lactosyl(β) Ceramide (d18:1/8:0) may be used to disrupt brain-derived neurotropic factor (BDNF)-induced integrin clustering.[1]
生化/生理作用
C8 L-threo-Lactosyl(β) Ceramide (d18:1/8:0) is a caveolar uptake inhibitor, which blocks SV40 virus infection. It also prevents E1-integrin activation and downstream signaling.[1] C8 L-threo-Lactosyl(β) Ceramide (d18:1/8:0) can deter the aggregation of lipids and proteins into glycosphingolipids (GSLs) and cholesterol-enriched microdomains (rafts) at the plasma membrane (PM).
包裝
5 mL Amber Glass Screw Cap Vial (860575P-1mg)
法律資訊
Avanti Research is a trademark of Avanti Polar Lipids, LLC
儲存類別代碼
11 - Combustible Solids
水污染物質分類(WGK)
WGK 3
Bidirectional remodeling of beta1-integrin adhesions during chemotropic regulation of nerve growth
Carlstrom LP, et al.
BMC biology, 9(1), 82-82 (2011)
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