860470P

1-deoxysphingosine

Avanti Research^™ - A Croda Brand 860470P, powder

• 同義詞: 1-deoxysphingosine (m18:1)
• 經驗公式（希爾表示法）: C₁₈H₃₇NO
• CAS號碼: 193222-34-3
• 分子量：: 283.49
• MDL號碼: MFCD22416646
• 分類程式碼代碼: 12352211
• NACRES: NA.25

屬性

• 形狀: powder
• 包裝: pkg of 1 × 1 mg (860470P-1mg); pkg of 1 × 10 mg (860470P-10mg)
• 製造商／商標名: Avanti Research^™ - A Croda Brand 860470P
• 脂質類型: bioactive lipids; sphingolipids
• 運輸包裝: dry ice
• 儲存溫度: −20°C
• SMILES 字串: C[C@@](N)([H])[C@]([H])(O)/C=C/CCCCCCCCCCCCC
• InChI 密鑰: ZREXGWPJFRJAJU-SWESGNQDSA-N

描述

一般說明

1-deoxysphingosine (1-deoxySO) has a (4E) double bond in its structure and is synthesized by the catabolism of 1-deoxyceramide in the presence of ceramidase enzyme.[1] It is an unsaturated deoxy-sphingoid base.[2]

應用

1-deoxysphingosine may be used for the complex preparation with bovine serum albumin for cytotoxicity testing of MN9D dopaminergic neuroblastoma cell line[3] and dorsal root ganglion neurons cultures.[2] It may also be used as a standard for quantification of spingolipids from human plasma samples by liquid chromatography electrospray ionization tandem mass spectrometry (LC−ESI−MS/MS).[4]

生化／生理作用

1-deoxysphingosine levels are elevated in lymphoblasts in hereditary sensory neuropathy type 1 (HSAN1) disorder.[2]

包裝

5 mL Amber Glass Screw Cap Vial (860470P-10mg)

5 mL Amber Glass Screw Cap Vial (860470P-1mg)

法律資訊

Avanti Research is a trademark of Avanti Polar Lipids, LLC

安全資訊

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3