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850482P

Avanti

16:0-18:0 (11-12BR) PC

1-palmitoyl-2-(11,12-dibromo)stearoyl-sn-glycero-3-phosphocholine, powder

同義詞:

1-hexadecanoyl-2-(11,12-dibromooctadecanoyl)-sn-glycero-3-phosphocholine

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About This Item

經驗公式（希爾表示法）:
C42H82NO8PBr2
CAS號碼:
324054-54-8
分子量：:
919.88
MDL號碼:
MFCD00674336
分類程式碼代碼:
12352211
NACRES:
NA.25
暫時無法取得訂價和供貨情況

化驗

>99% (TLC)

形狀

powder

包裝

pkg of 1 × 10 mg (850482P-10mg)

製造商／商標名

Avanti Research™ - A Croda Brand 850482P

脂質類型

phospholipids
omega FAs

運輸包裝

dry ice

儲存溫度

−20°C

SMILES 字串

[O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCCCCC(Br)C(Br)CCCCCC)=O)COC(CCCCCCCCCCCCCCC)=O)=O

InChI

1S/C42H82Br2NO8P/c1-6-8-10-12-13-14-15-16-17-18-21-24-28-32-41(46)50-36-38(37-52-54(48,49)51-35-34-45(3,4)5)53-42(47)33-29-25-22-19-20-23-27-31-40(44)39(43)30-26-11-9-7-2/h38-40H,6-37H2,1-5H3/t38-,39?,40?/m1/s1

InChI 密鑰

MPQPFPFIGLVSQR-YXGYHMDESA-N

一般說明

16:0-18:0 (11-12BR) PC (1-palmitoyl-2-(11,12-dibromo) stearoyl-sn-glycero-3-phosphocholine) is a brominated-PC lipid[1] which has palmitoyl and stearoyl chains.

應用

16:0-18:0 (11-12BR) PC (1-palmitoyl-2-(11,12-dibromo) stearoyl-sn-glycero-3-phosphocholine) has been used in large unilamellar vesicle preparation.[2] It may be used:
  • in phospholipid vesicle preparation for tryptophan (Trp) penetration depth experiments[1]
  • to determine the bromination effect at different positions along the fatty acid chains[3]
  • in large unilamellar vesicle (LUV) for quenching of human heat shock protein 70 (Hsp70) tryptophan (Trp) fluorescence[4]

生化／生理作用

16:0-18:0 (11-12BR) PC (1-palmitoyl-2-(11,12-dibromo) stearoyl-sn-glycero-3-phosphocholine) can be used to prepare large unilamellar vesicles.[2]

包裝

5 mL Clear Glass Sealed Ampule (850482P-10mg)

法律資訊

Avanti Research is a trademark of Avanti Polar Lipids, LLC

儲存類別代碼

11 - Combustible Solids

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分析證明 (COA)

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Ajay K Mahalka et al.
Biochimica et biophysica acta, 1838(5), 1344-1361 (2014-02-01)
While a significant fraction of heat shock protein 70 (Hsp70) is membrane associated in lysosomes, mitochondria, and the outer surface of cancer cells, the mechanisms of interaction have remained elusive, with no conclusive demonstration of a protein receptor. Hsp70 contains
Henriette Aksnes et al.
The Journal of biological chemistry, 292(16), 6821-6837 (2017-02-16)
Nα-Acetyltransferase 60 (Naa60 or NatF) was recently identified as an unconventional N-terminal acetyltransferase (NAT) because it localizes to organelles, in particular the Golgi apparatus, and has a preference for acetylating N termini of the transmembrane proteins. This knowledge challenged the
Tim Rasmussen et al.
Journal of molecular biology, 431(17), 3339-3352 (2019-06-08)
All membrane proteins have dynamic and intimate relationships with the lipids of the bilayer that may determine their activity. Mechanosensitive channels sense tension through their interaction with the lipids of the membrane. We have proposed a mechanism for the bacterial
Candace M Pfefferkorn et al.
Biochimica et biophysica acta, 1848(11 Pt A), 2821-2828 (2015-08-25)
Apolipoproteins are essential human proteins for lipid metabolism. Together with phospholipids, they constitute lipoproteins, nm to μm sized particles responsible for transporting cholesterol and triglycerides throughout the body. To investigate specific protein-lipid interactions, we produced and characterized three single-Trp containing

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