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850476C

Avanti

18:1-18:0 PC

1-oleoyl-2-stearoyl-sn-glycero-3-phosphocholine, chloroform

同義詞:

1--(9Z-octadecenoyl)-2-octadecanoyl-sn-glycero-3-phosphocholine; OSPC; PC(18:1(9Z)/18:0)

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About This Item

經驗公式(希爾表示法):
C44H86NO8P
CAS號碼:
分子量::
788.13
MDL號碼:
分類程式碼代碼:
51191904
NACRES:
NA.25
暫時無法取得訂價和供貨情況

化驗

>99% (TLC)

形狀

liquid

包裝

pkg of 1 × 2.5 mL (850476C-25mg)

製造商/商標名

Avanti Research - A Croda Brand 850476C

濃度

10 mg/mL (850476C-25mg)

脂質類型

cardiolipins
phospholipids

運輸包裝

dry ice

儲存溫度

−20°C

SMILES 字串

[P](=O)([O-])(OC[C@H](OC(=O)CCCCCCCCCCCCCCCCC)COC(=O)CCCCCCC\C=C/CCCCCCCC)OCC[N+](C)(C)C

InChI

1S/C44H86NO8P/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-34-36-43(46)50-40-42(41-52-54(48,49)51-39-38-45(3,4)5)53-44(47)37-35-33-31-29-27-25-23-21-19-17-15-13-11-9-7-2/h20,22,42H,6-19,21,23-41H2,1-5H3/b22-20-/t42-/m1/s1

InChI 密鑰

NMJCSTNQFYPVOR-VHONOUADSA-N

一般說明

18:1-18:0 PC (1-oleoyl-2-stearoyl-sn-glycero-3-phosphocholine) is an asymmetric phospholipid.[1]

應用

18:1-18:0 PC (1-oleoyl-2-stearoyl-sn-glycero-3-phosphocholine) may be used:
  • as a lipid standard in ultra-performance liquid chromatography (UPLC) analyses[2]
  • in bilayer membranes to study the bilayer phase transitions[1]
  • in liposome as substrate to study the transacylase activities of different lysosomal phospholipase A2 (LPLA2) variants[3]

生化/生理作用

Phosphatidylcholine (PC) is known to participate in fusion and transport of membranes.[4]

包裝

5 mL Clear Glass Sealed Ampule (850476C-25mg)

法律資訊

Avanti Research is a trademark of Avanti Polar Lipids, LLC

象形圖

Skull and crossbonesHealth hazard

訊號詞

Danger

危險分類

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

標靶器官

Central nervous system, Liver,Kidney

水污染物質分類(WGK)

WGK 3


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分析證明 (COA)

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Kaori Tada et al.
Biochimica et biophysica acta, 1788(5), 1056-1063 (2009-02-24)
The bilayer phase transitions of six kinds of mixed-chain phosphatidylcholines (PCs) with an unsaturated acyl chain in the sn-1 or sn-2 position, 1-oleoyl-2-stearoyl- (OSPC), 1-stearoyl-2-oleoyl- (SOPC), 1-oleoyl-2-palmitoyl- (OPPC), 1-palmitoyl-2-oleoyl- (POPC), 1-oleoyl-2-myristoyl- (OMPC) and 1-myristoyl-2-oleoyl-sn-glycero-3-phosphocholine (MOPC), were observed by means of
Katharina Wozny et al.
Analytical and bioanalytical chemistry, 411(4), 915-924 (2018-12-24)
Diacyl glycerophospholipids (GPs) belong to the most abundant lipid species in living organisms and consist of a glycerol backbone with fatty acyl groups in sn-1 and sn-2 and a polar head group in the sn-3 position. Regioisomeric mixed diacyl GPs
Vania Hinkovska-Galcheva et al.
Journal of lipid research, 59(7), 1205-1218 (2018-05-05)
Lysosomal phospholipase A2 (LPLA2) is characterized by broad substrate recognition, peak activity at acidic pH, and the transacylation of lipophilic alcohols, especially N-acetyl-sphingosine. Prior structural analysis of LPLA2 revealed the presence of an atypical acidic residue, Asp13, in the otherwise
Miao-Miao Zhou et al.
Lipids in health and disease, 15(1), 135-135 (2016-08-26)
Phosphatidylcholine (PC), the major source of dietary choline, has been demonstrated to improve the capability of learning and memory in rodent and the amelioration of long-chain n-3 polyunsaturated fatty acids (PUFA) on anti-aging and anti-oxidation is widely known as well.
Simon Becher et al.
Analytical chemistry, 90(19), 11486-11494 (2018-09-11)
Phosphatidylcholines are the major phospholipid component of most eukaryotic cell membranes. Phosphatidylcholines have been shown to actively participate in regulatory and metabolic processes. Dysfunctional metabolic processes have been linked to human disease and can result in altered phosphatidylcholine structural features

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