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840039P

Avanti

18:0-18:1 PS

1-stearoyl-2-oleoyl-sn-glycero-3-phospho-L-serine (sodium salt), powder

同義詞:

1-十八烷酰基-2-（9Z-十八烯酰基）-sn-甘油-3-磷酸-L-丝氨酸（钠盐）；SOPS；PS(18:0/18:1(9Z))；110672

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About This Item

經驗公式（希爾表示法）:
C42H79NO10PNa
CAS號碼:
321883-23-2
分子量：:
812.04
分類程式碼代碼:
51191904
NACRES:
NA.25
暫時無法取得訂價和供貨情況

化驗

>99% (TLC)

形狀

powder

包裝

pkg of 1 × 10 mg (840039P-10mg)
pkg of 2 × 100 mg (840039P-200mg)

製造商／商標名

Avanti Research™ - A Croda Brand 840039P

脂質類型

phospholipids
cardiolipins

運輸包裝

dry ice

儲存溫度

−20°C

SMILES 字串

[H][C@@](COP([O-])(OC[C@](C([O-])=O)([H])[NH3+])=O)(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCCCCCCCCCCCC)=O.[Na+]

InChI

1S/C42H80NO10P.Na/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-40(44)50-35-38(36-51-54(48,49)52-37-39(43)42(46)47)53-41(45)34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2;/h18,20,38-39H,3-17,19,21-37,43H2,1-2H3,(H,46,47)(H,48,49);/q;+1/p-1/b20-18-;/t38-,39+;/m1./s1

InChI 密鑰

ALPKKMIPHGSQRX-NJZWBUMZSA-M

相關類別

一般說明

18:0-18:1 PS（1-硬脂酰基-2-油酰基-sn-甘油-3-磷酸-L-丝氨酸）是以磷酸丝氨酸为骨架的修饰脂质的钠盐。

應用

18:0-18:1 PS（1-硬脂酰基-2-油酰基-sn-甘油-3-磷酸-L-丝氨酸（钠盐））：
  • 已用于制备多层和单层脂质体[1]
  • 可用于制备用于脂质体结合测定的脂质体[2]
  • 可用于产生多层磷脂囊泡[3]

生化／生理作用

磷脂酰丝氨酸（PS）在蛋白激酶C途径中起关键作用。[4]

包裝

5 mL透明玻璃密封安瓿（840039P-10mg）
5 mL透明玻璃密封安瓿（840039P-200mg）

法律資訊

Avanti Research is a trademark of Avanti Polar Lipids, LLC

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產品號碼
描述
訂價

儲存類別代碼

11 - Combustible Solids

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分析證明 (COA)

Lot/Batch Number

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Julie K Freed et al.
Endothelium : journal of endothelial cell research, 15(4), 225-230 (2008-07-30)
Previous studies have demonstrated that endothelial cells exposed to laminar shear stress are protected from apoptotic stimuli such as tumor necrosis factor (TNF)-alpha. The authors investigated the role of phosphatidylserine (PS) in this phenomenon. Western blot analysis of cleaved caspase
Kristof Schutters et al.
Apoptosis : an international journal on programmed cell death, 15(9), 1072-1082 (2010-05-05)
Cells are able to execute apoptosis by activating series of specific biochemical reactions. One of the most prominent characteristics of cell death is the externalization of phosphatidylserine (PS), which in healthy cells resides predominantly in the inner leaflet of the
Katarzyna Gajos et al.
Analytical and bioanalytical chemistry, 409(4), 1109-1119 (2016-11-09)
Among the various biomarkers that are used to diagnose or monitor disease, extracellular vesicles (EVs) represent one of the most promising targets in the development of new therapeutic strategies and the application of new diagnostic methods. The detection of circulating
Anne Jäkel et al.
Protein & cell, 1(2), 188-197 (2011-01-05)
The role of surfactant protein A (SP-A) in the recognition and clearance of apoptotic cells is well established, but to date, it is still not clear which surface molecules of apoptotic cells are involved in the process. Here we present
John M Harrington et al.
The Journal of biological chemistry, 289(36), 24811-24820 (2014-07-20)
Haptoglobin-related protein (Hpr) is a component of a minor subspecies of high density lipoproteins (HDL) that function in innate immunity. Here we show that assembly of Hpr into HDL is mediated by its retained N-terminal signal peptide, an unusual feature
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