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重要文件

810133C

Avanti

18:1-12:0 NBD PC

Avanti Research™ - A Croda Brand 810133C

同義詞:

1-Oleoyl-2-[12-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]dodecanoyl]-sn-Glycero-3-Phosphocholine

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About This Item

經驗公式（希爾表示法）:
C44H76N5O11P
CAS號碼:
190792-36-0
分子量：:
882.07
MDL號碼:
MFCD22495265
分類程式碼代碼:
12352211
NACRES:
NA.25
暫時無法取得訂價和供貨情況

化驗

>99% (TLC)

形狀

liquid

包裝

pkg of 1 × 1 mL (810133C-1mg)
pkg of 5 × 1 mL (810133C-5mg)

製造商／商標名

Avanti Research™ - A Croda Brand 810133C

濃度

1 mg/mL (810133C-1mg)
1 mg/mL (810133C-5mg)

脂質類型

fluorescent lipids
phospholipids

運輸包裝

dry ice

儲存溫度

−20°C

相關類別

一般說明

Phosphatidylcholine (PC) is a prime metabolite in eukaryotes glycerolipid metabolism,[1] mainly synthesized in liver.[2] It is a major element of lipoproteins, bile and lung surfactant.[2] NBD PC contains 7-nitrobenz-2-oxa-1,3-diazol-4-yl (NBD) covalently attached to phosphatidylcholine.[3]

應用

18:1-06:0 NBD PC is suitable for:
  • the generation giant unilamellar vesicles (GUVs) subjected to fluorescence microscopy[4]
  • labelling lipid bilayers formed by vesicle fusion in order to study the lipid distribution by fluorescence microscopy[5]
  • the preparation of phospholipid-coated beads[6]

生化／生理作用

7-nitrobenz-2-oxa-1,3-diazol-4-yl phosphatidylcholine (NBD PC) functions as a fluorescent analog in biological membranes in order to study the cellular processes.[3]

包裝

5 mL Amber Glass Screw Cap Vial (810133C-1mg)
5 mL Amber Glass Screw Cap Vial (810133C-5mg)

法律資訊

Avanti Research is a trademark of Avanti Polar Lipids, LLC

象形圖

Skull and crossbonesHealth hazard
GHS06,GHS08

訊號詞

Danger

危險分類

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

標靶器官

Central nervous system, Liver,Kidney

水污染物質分類（WGK）

WGK 3

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分析證明 (COA)

Lot/Batch Number

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Laura K Cole et al.
Biochimica et biophysica acta, 1821(5), 754-761 (2011-10-08)
Phosphatidylcholine (PC) is the major phospholipid component of all plasma lipoprotein classes. PC is the only phospholipid which is currently known to be required for lipoprotein assembly and secretion. Impaired hepatic PC biosynthesis significantly reduces the levels of circulating very
Sang-Yeob Kim et al.
PloS one, 12(4), e0174603-e0174603 (2017-04-05)
The removal of unwanted or damaged cells by phagocytes is achieved via a finely regulated cleaning process called efferocytosis. To characterize the mechanisms through which phagocytes control the intake of apoptotic cells, we investigated how the phagocyte's appetite for engulfed
Haijia Yu et al.
Proceedings of the National Academy of Sciences of the United States of America, 113(16), 4362-4367 (2016-04-05)
Organelles are in constant communication with each other through exchange of proteins (mediated by trafficking vesicles) and lipids [mediated by both trafficking vesicles and lipid transfer proteins (LTPs)]. It has long been known that vesicle trafficking can be tightly regulated
Henry A Boumann et al.
Biochimica et biophysica acta, 1788(7), 1444-1451 (2009-04-21)
Anammox bacteria that are capable of anaerobically oxidizing ammonium (anammox) with nitrite to nitrogen gas produce unique membrane phospholipids that comprise hydrocarbon chains with three or five linearly condensed cyclobutane rings. To gain insight into the biophysical properties of these
Wan-Chen Lin et al.
Biophysical journal, 90(1), 228-237 (2005-10-11)
A fundamental attribute of cell membranes is transmembrane asymmetry, specifically the formation of ordered phase domains in one leaflet that are compositionally different from the opposing leaflet of the bilayer. Using model membrane systems, many previous studies have demonstrated the
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