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重要文件

810128C

Avanti

12:0 Lyso NBD PC

Avanti Research™ - A Croda Brand 810128C

同義詞:

1-{12-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]dodecanoyl}-2-hydroxy-sn-glycero-3-phosphocholine

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About This Item

經驗公式（希爾表示法）:
C26H44N5O10P
CAS號碼:
1246303-00-3
分子量：:
617.63
分類程式碼代碼:
12352211
NACRES:
NA.25
暫時無法取得訂價和供貨情況

化驗

>99% (LPC; may contain up to 10% of the 2-LPC isomer, TLC)

形狀

liquid

包裝

pkg of 1 × 1 mL (810128C-1mg)
pkg of 5 × 1 mL (810128C-5mg)

製造商／商標名

Avanti Research™ - A Croda Brand 810128C

濃度

1 mg/mL (810128C-1mg)
1 mg/mL (810128C-5mg)

脂質類型

fluorescent lipids

運輸包裝

dry ice

儲存溫度

−20°C

應用

12:0 Lyso NBD PC may be used as a substrate to measure the enzymatic activity of recombinant human lysophosphatidylcholine acyltransferase 3 (rhLPCAT3)[1] and to study the function of lysophosphatidic acid (LPA) as an inhibitor in the autotaxin (ATX) catalysis.[2]

包裝

5 mL Clear Glass Sealed Ampule (810128C-1mg)
5 mL Clear Glass Sealed Ampule (810128C-5mg)

法律資訊

Avanti Research is a trademark of Avanti Polar Lipids, LLC

象形圖

Skull and crossbonesHealth hazard
GHS06,GHS08

訊號詞

Danger

危險分類

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

標靶器官

Central nervous system

儲存類別代碼

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

水污染物質分類（WGK）

WGK 3

閃點（°F）

does not flash

閃點（°C）

does not flash

從最近期的版本中選擇一個：

分析證明 (COA)

Lot/Batch Number

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Fernando Salgado-Polo et al.
The Journal of biological chemistry, 293(37), 14312-14327 (2018-07-22)
Autotaxin (ATX) is a secreted glycoprotein and the only member of the ectonucleotide pyrophosphatase/phosphodiesterase family that converts lysophosphatidylcholine (LPC) into lysophosphatidic acid (LPA). LPA controls key responses, such as cell migration, proliferation, and survival, implicating ATX-LPA signaling in various (patho)physiological
Lauren P Saunders et al.
The Journal of biological chemistry, 286(34), 30130-30141 (2011-07-02)
Autotaxin (ATX) is a secreted lysophospholipase D that hydrolyzes lysophosphatidylcholine (LPC) into lysophosphatidic acid (LPA), initiating signaling cascades leading to cancer metastasis, wound healing, and angiogenesis. Knowledge of the pathway and kinetics of LPA synthesis by ATX is critical for
Xinming Du et al.
FEBS open bio, 9(10), 1734-1743 (2019-08-04)
Lysophosphatidylcholine acyltransferase 3 (LPCAT3) is an important enzyme in phospholipid remodeling, a process that influences the biophysical properties of cell membranes and thus cell function. Multiple lines of evidence suggest that LPCAT3 is involved in several diseases, including atherosclerosis, non-alcoholic
Stephen M Baumler et al.
Langmuir : the ACS journal of surfaces and colloids, 33(12), 2986-2992 (2017-03-08)
The translational diffusion dynamics of the zwitterionic lipid 1,2-dimyristoyl-sn-glycero-3-phosphocholine (DMPC) at a planar phosphorylated support surface containing metal ions (Mg2+, Ca2+, Ba2+, Ni2+, Zn2+, Cd2+, Zr4+) was investigated using X-ray photoelectron spectroscopy (XPS) and fluorescence recovery after photobleaching (FRAP). Fluorescence

文章

Critical Micelle Concentrations (CMCs) - Avanti® Polar Lipids

The critical micelle concentration (CMC) can be approximately defined as the lipid monomer concentration at which appreciable amounts (>5% of total) of micellar aggregates first begin to appear in the equilibrium: nM1<=>Mn

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