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重要文件

791645C

Avanti

18:1-d7-cholesterol

Avanti Research - A Croda Brand 791645C

同義詞:

cholest-5-en-3β-yl oleate-d7

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About This Item

經驗公式(希爾表示法):
C45H71 D7O2
CAS號碼:
分子量::
658.14
MDL號碼:
分類程式碼代碼:
41141804
NACRES:
NA.25
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化驗

>99% (TLC)

形狀

liquid

包裝

pkg of 1 × 1 mL (791645C-1mg)

製造商/商標名

Avanti Research - A Croda Brand 791645C

濃度

1 mg/mL (791645C-1mg)

運輸包裝

dry ice

儲存溫度

−20°C

一般說明

Cholesteryl oleate is a cholesteryl ester.[1] 18:1-d7-cholesterol is a deuterated oleic acid cholesteryl ester.
This deuterium labeled lipid is also available in a formulation of multiple lipid standards. The SPLASH LIPIDOMIX Standard includes all of the major lipid classes at ratios relative to human plasma, allowing one easy internal standard solution to be added to every sample.

應用

18:1-d7-cholesterol may be used in the reconstitution of acetylated low-density lipoprotein (acLDL) liposome for trafficking studies in U2OS-SRA cells.[2]

生化/生理作用

Elevation in cholesterol ester levels and its accumulation is implicated in prostate cancer (PCa). Cholesteryl oleate, may serve as a potential biomarker for diagnosis of PCa.[3]

包裝

5 mL Clear Glass Sealed Ampule (791645C-1mg)

法律資訊

Avanti Research is a trademark of Avanti Polar Lipids, LLC
LIPIDOMIX is a trademark of Avanti Polar Lipids, LLC
SPLASH is a trademark of Avanti Polar Lipids, LLC

象形圖

Skull and crossbonesHealth hazard

訊號詞

Danger

危險分類

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

標靶器官

Central nervous system, Liver,Kidney

水污染物質分類(WGK)

WGK 3


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Lot/Batch Number

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Jia Li et al.
Scientific reports, 6, 20984-20984 (2016-02-13)
In-depth delineation of lipid metabolism in prostate cancer (PCa) is significant to open new insights into prostate tumorigenesis and progression, and provide potential biomarkers with greater accuracy for improved diagnosis. Here, we performed lipidomics and transcriptomics in paired prostate cancer
Heart Proteomics, 967-1009 (2001)
McKenna Feltes et al.
Journal of lipid research, 60(3), 707-716 (2019-01-09)
Cholesterol is an essential structural component of cellular membranes and precursor molecule for oxysterol, bile acid, and hormone synthesis. The study of intracellular cholesterol trafficking pathways has been limited in part due to a lack of suitable cholesterol analogues. Herein

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